ISSN 1004-4140
CN 11-3017/P

周围型小肺癌动态增强MRI与18F FDG PET/CT的相关性初探

冯峰, 夏淦林, 强福林, 施冬辉, 沈爱军, 傅爱燕, 李海明, 张明珠

冯峰, 夏淦林, 强福林, 施冬辉, 沈爱军, 傅爱燕, 李海明, 张明珠. 周围型小肺癌动态增强MRI与18F FDG PET/CT的相关性初探[J]. CT理论与应用研究, 2017, 26(4): 467-472. DOI: 10.15953/j.1004-4140.2017.26.04.08
引用本文: 冯峰, 夏淦林, 强福林, 施冬辉, 沈爱军, 傅爱燕, 李海明, 张明珠. 周围型小肺癌动态增强MRI与18F FDG PET/CT的相关性初探[J]. CT理论与应用研究, 2017, 26(4): 467-472. DOI: 10.15953/j.1004-4140.2017.26.04.08
FENG Feng, XIA Gan-lin, QIANG Fu-lin, SHI Dong-hui, SHEN Ai-jun, FU Ai-yan, LI Hai-ming, ZHANG Ming-zhu. A Preliminary Study of Correlation between Dynamic Contrast Enhancement MRI and 18F-FDG PET/CT in Small Peripheral Lung Cancer[J]. CT Theory and Applications, 2017, 26(4): 467-472. DOI: 10.15953/j.1004-4140.2017.26.04.08
Citation: FENG Feng, XIA Gan-lin, QIANG Fu-lin, SHI Dong-hui, SHEN Ai-jun, FU Ai-yan, LI Hai-ming, ZHANG Ming-zhu. A Preliminary Study of Correlation between Dynamic Contrast Enhancement MRI and 18F-FDG PET/CT in Small Peripheral Lung Cancer[J]. CT Theory and Applications, 2017, 26(4): 467-472. DOI: 10.15953/j.1004-4140.2017.26.04.08

周围型小肺癌动态增强MRI与18F FDG PET/CT的相关性初探

基金项目: 

南通市科技局资助项目(MS22015107);南通市卫生局青年基金资助项目(WQ2014047)。

详细信息
    作者简介:

    冯峰(1976-),男,南通市肿瘤医院影像科副主任医师,博士,硕士生导师,研究方向为胸部疾病影像诊断,Tel:15851201758,E-mail:drfengfeng@163.com;夏淦林*(1956-),男,南通市肿瘤医院影像科副教授,副主任医师,主要从事肿瘤影像诊断的研究,Tel:13951324621,E-mail:ntxgl008@aliyun.com。

  • 中图分类号: R812;R445

A Preliminary Study of Correlation between Dynamic Contrast Enhancement MRI and 18F-FDG PET/CT in Small Peripheral Lung Cancer

  • 摘要: 目的:探讨周围型小肺癌动态增强磁共振成像(DCE-MRI)定量参数和18F-2-脱氧葡萄糖正电子体层摄影/计算机体层摄影(18F FDG PET/CT)最大标准摄取值(SUVmax)的相关性。方法:27例最大径 ≤ 3 cm的周围型小肺癌行18F FDG PET/CT及动态增强MR扫描。测量磁共振定量参数容量转运常数(Ktrans)、回流速率常数(Kep)、细胞外对比剂容积分数(Ve)及PET/CT最大标准摄取值(SUVmax)。比较动态增强MRI三个定量参数值与SUVmax的相关性。结果:DCE-MRI的定量参数Ktrans值、Kep值分别与PET/CT半定量参数SUVmax之间存在正相关(P<0.05);而Ve与SUVmax无相关性(P>0.05)。结论:DCE-MRI定量参数Ktrans值及Kep值与SUVmax正相关,三者可共同反映周围型小肺癌的恶性特征。
    Abstract: Objective: To investigate the correlations of the dynamic contrast enhancement MRI (DCE-MRI) and glucose metabolism determined by the maximum standardized uptake value (SUVmax) at 18F-FDG PET/CT in small peripheral cell lung cancer. Methods: 18F-FDG PET/CT and DCE-MRI wereperformed in 27 consecutive patients with histologically verifiedsmall peripherallung cancer (maximal diameter ≤ 3 cm). The quantitative MR pharmaeokineticparameters including Ktrans, Kep, Ve and SUVmax were measured. Pearson's correlations were conducted between the three MR parameters and SUVmax.Results: Positive correlations were found between Ktrans and SUV max, Kep and SUVmax (P < 0.05). No significant correlation was found for thecomparison of Ve and SUV max (P>0.05). Conclusions: Positive correlationswere found between Ktrans and SUVmax, Kep and SUVmax. Combination of three parameters can reflect the malignant feature of lung cancer.
  • 期刊类型引用(6)

    1. 海江,张海莲,杨慧. 肺癌肿瘤血管生成DCE-MRI参数与IGF1表达的相关性. 中国CT和MRI杂志. 2023(02): 61-63 . 百度学术
    2. 柴广金,李围围,吕博,许曼. PET/CT代谢参数与LMR在评估肺癌放化疗近期疗效的临床研究. 中国CT和MRI杂志. 2021(08): 54-56 . 百度学术
    3. 李宇鸣,骆顺娣,黄志敏,罗素云. CT引导下经皮肺穿刺活检诊断周围型肺癌的临床应用及对咯血发生率的影响. 现代医用影像学. 2020(05): 791-796 . 百度学术
    4. 傅炎炎,姬颖华,杨小昱. 早期周围型小肺癌HRCT检查的图像分析. 深圳中西医结合杂志. 2020(14): 61-62 . 百度学术
    5. 冯凯,杨瑜玲,孙溯,廖琰彬. MRI联合CT影像学在肺癌中的诊断效能. 癌症进展. 2019(13): 1512-1514+1525 . 百度学术
    6. 尚来换. CT、MRI对周围型肺癌的诊断研究. 现代医用影像学. 2019(11): 2459-2460 . 百度学术

    其他类型引用(0)

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  • 被引次数: 6
出版历程
  • 收稿日期:  2017-01-08
  • 网络出版日期:  2022-11-30
  • 发布日期:  2017-08-24

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