Abstract: Objective: To analyze the value of 64 slice spiral CT and DSA in evaluating the degree of patency and stenosis after coronary artery stent implantation. Methods: 250 patients with acute coronary syndromes treated in our hospital from January 2013 to April 2018 were selected as the subjects of this group. 64 layers of spiral CT and DSA were used to evaluate the degree of patency and stenosis after coronary stent implantation in patients with acute coronary syndromes. The evaluation value of both was analyzed. Results: There was no significant difference in coronary artery imaging scores of different sites by 64 slice spiral CT and DSA (P>0.05). 64 layers of spiral CT and DSA were used for coronary artery imaging score of different diameter stents (P>0.05). 64 layers of spiral CT and DSA examination were used for different scaffolds. There was no significant difference in the results of the arteriography score (P>0.05); 96 stents were placed in 52 patients. The patients were examined with 64 spirals CT and DSA. The results showed that there was no statistical difference between 64 layers of spiral CT and DSA (P>0.05). Conclusions: 64 rows of spiral CT coronary angiography were used to evaluate the degree of patency and stenosis after coronary stent implantation in patients with acute coronary syndromes and the results were in high agreement with the results of DSA.