Study of Energy Spectrum CT Virtual Non-contrast in Subsolid Lung Adenocarcinoma
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摘要: 目的：评价能谱CT虚拟平扫与常规CT扫描对亚实性肺腺癌密度（CT值）的一致性；增强扫描对亚实性肺腺癌侵袭性判断的价值。方法：46例患者胸部CT平扫首次发现肺部亚实性结节患者行能谱CT增强扫描，符合条件39例患者共45个经病理证实为肺腺癌及其癌前病变入组。在工作站获取虚拟平扫图像，比较病灶、周围正常肺组织及椎旁肌各组能谱数据感兴趣区的平均HU值有无差异及其相关性；根据预后及侵袭性分为癌前病变及微浸润性腺癌组、浸润性腺癌组并比较两者的差异。结果：病灶、周围肺组织及椎旁肌的普通平扫与虚拟平扫CT净增值之间无显著差异，且两者具有高度相关性。HU净增值及碘浓度在癌前病变及微浸润性腺癌组、浸润性腺癌组之间无显著差异，增强扫描在鉴别肺腺癌浸润性方面无阳性结果。结论：应用能谱CT虚拟平扫HU值与普通平扫无统计学差异并显著相关，增强扫描对鉴别肺腺癌浸润性方面无阳性结果。Abstract: Objectives: To evaluate the consistency of energy spectrum CT virtual non-contrast and non-contrast scan on the density of subsolid lung adenocarcinoma (CT value); and the value of enhancement scan on the invasiveness of subsolid lung adenocarcinoma. Methods: 46 patients with subsolid nodules on chest CT first time and then scanning spectrum CT enhancement. A total of 45 nodules with pathologically confirmed lung adenocarcinoma and precancerous lesions were enrolled in 39 patients. Obtain virtual non-contrast images at the workstation, compare the average HU values of the regions of interest in the lesions, surrounding normal lung tissue and paravertebral muscles. According to the prognosis and invasiveness, divided into the precancerous lesions, the minimally invasive adenocarcinoma group and the invasive adenocarcinoma group, which compared there difference. Results: There was no significant difference between the non-contrast and virtual non-contrast of the surrounding normal lung tissues and paravertebral muscles, which were highly correlated. There was no significant difference in HU and iodine concentration. There was no positive results in the invasiveness of lung adenocarcinoma between the groups of the precancerous lesions, the minimally invasive adenocarcinoma and the invasive adenocarcinoma. Conclusion: There was no statistically significant difference between the energy spectrum CT virtual non-contrast HU value and the non-contrast scan. The enhancement scan had no positive results in identifying the invasiveness of lung adenocarcinoma in this group.
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期刊类型引用(4)
1. 洪静静，文戈，张飞，张莲莲，刘迪斯，黄伟康. 基于能谱CT虚拟平扫与常规平扫在肺内部分实性结节图像质量的对照研究. 分子影像学杂志. 2024(05): 528-532 . 
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2. 栗鸿宝，朱美婕，孙兴智. 能谱CT虚拟平扫在肺结节及肿块评价中的应用. 山西医药杂志. 2021(03): 375-377 . 百度学术
3. 陈疆红，钟朝辉，王大为，杨正汉，王振常，江桂莲. 能谱CT虚拟平扫在肺结节AI辅助诊断系统预测亚实性结节恶性概率中的应用. 放射学实践. 2020(08): 972-977 . 百度学术
4. 陈雄钊，黄金爱，李顺长，滕录霞，张远鸿，郭伟斌，张世林. 胸部CT多期增强扫描在CT引导下肺穿刺活检术前评估价值. 实用医技杂志. 2020(09): 1155-1157 . 百度学术
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