Feasibility Analysis of MCTSI Combined with D-dimmer in Evaluating the Clinical Prognosis of Patients with Acute Pancreatitis
-
摘要: 目的：评估MCTSI评分联合D-二聚体检测值与急性胰腺炎患者临床预后的相关性。方法：收集我院2016年8月至2018年1月间收治并确诊的急性胰腺炎患者150例，记录入院后首日血浆D-二聚体检测值，并于第5~7日行CT增强扫描检查，根据MCTSI标准进行评分，将MCTSI评分和血浆D-二聚体检测值经过Logistic回归方程得出联合检测值，并将MCTSI评分、D-二聚体检测值、联合检测值进行ROC曲线分析。结果：轻、中、重度急性胰腺炎患者血浆D-二聚体检测值及预后存在有明显差异（P<0.001），重度患者D-二聚体检测值显著高于轻、中度患者（P<0.001）。MCTSI评分和血浆D-二聚体检测值经过Logistic回归方程得出联合检测值对于患者器官功能衰竭预测的效能优于单独使用MCTSI评分及血浆D-二聚体检测值预测的效能，且其与住院天数的相关系数也最高。结论：针对急性胰腺炎患者，参照MCTSI以及D-二聚体检测值进行联合评估，可了解患者预后情况，具备较高的临床参考价值。Abstract: Objective: Assessing the correlation between MCTSI score combined with D-dimer detection value and the clinical prognosis in patients with acute pancreatitis. Methods: 150 acute pancreatitis patients admitted to our hospital from August 2016 to January 2018 were collected. The plasma D-dimer detection value was recorded on the first day after admission. The CT enhancement scan was performed on the 5th to 7th day. According to the MCTSI standard, the combined detection value of MCTSI score and plasma D-dimer detection value was obtained by Logistic regression equation. MCTSI score, D-dimer detection value and combined detection value were analyzed by ROC curve. Results: There were significant differences in plasma D-dimer detection value and clinical prognosis among mild, moderate and severe acute pancreatitis patients (P<0.001). The D-dimer detection value in severe patients was significantly higher than that in mild and moderate patients (P<0.001). The combined detection value of MCTSI score and plasma D-dimer detection value obtained by Logistic regression equation is more effective in predicting organ failure than using MCTSI score and plasma D-dimer detection value alone, and it has the highest correlation coefficient with the length of hospital stay. MCTSI score combined with D-dimer detection value has high clinical reference value for clinical prognosis of acute pancreatitis patients. Conclusion: According to the combined evaluation of MCTSI and D-dimer detection value, we can understand the clinical prognosis of acute pancreatitis patients, which has a high clinical reference value.
-
Keywords:
- acute pancreatitis /
- MCTSI score /
- D-dimer /
- coagulation function
-
-
期刊类型引用(13)
1. 刘蕃荔，洪英，张宏，曹媛媛，龚喆嘉，雷方，王卓，庄瑞. CT评分系统联合MPV、RDW对急性胰腺炎患者预后的预测价值. 临床医学研究与实践. 2024(20): 18-21 . 
百度学术
2. 洪英，刘蕃荔，曹媛媛，张宏，韩升，张宁，王卓，袁伟. CT评分系统联合血尿淀粉酶对急性胰腺炎患者预后的预测价值. 临床医学研究与实践. 2023(31): 10-13 . 百度学术
3. 王婷，李文武，张桂凤. 螺旋CT灌注参数联合血清D-二聚体对急性胰腺炎患者病情严重程度及预后的预测作用. 国际医药卫生导报. 2022(15): 2160-2165 . 百度学术
4. 尹小勇，董科，杨正东，何显军，何鑫，郭润兮，赵芸芸，张克波. 乳酸、血浆D-二聚体、纤维蛋白原联合检测对高脂血症性胰腺炎严重程度及预后评价. 西部医学. 2021(07): 1001-1004+1015 . 百度学术
5. 尹雪军，徐才国，牛富业，刘林. CT和MRI对急性胰腺炎的临床诊断价值比较. 影像研究与医学应用. 2021(09): 31-32 . 百度学术
6. 杨宁，王瑞峰，耿金婷，王小兵. 白细胞和乳酸脱氢酶对急性胰腺炎MCTSI评分和预后关系的研究. 中国中西医结合消化杂志. 2021(08): 555-558 . 百度学术
7. 王霞，沈爱武，刘海云，徐珊. 三种CT评分对重症急性胰腺炎患者预后的评估价值. 贵州医科大学学报. 2021(12): 1483-1488 . 百度学术
8. 孔卓，刘武征，万极硕，张正. 血液AMY、FIB及SCr与老年急性胰腺炎患者MCTSI评分和预后关系的研究. 老年医学与保健. 2021(06): 1305-1308 . 百度学术
9. 王鲁，徐亭，王瑞峰，王小兵. BISAP和MCTSI对急性胰腺炎患者病情进展的预测价值. 医学研究杂志. 2021(12): 84-88 . 百度学术
10. 木塔里甫·买合木提，郭峻氚，肖东. 超声影像在重症胰腺炎病情评估中的应用价值. 中国医师杂志. 2020(04): 517-520 . 百度学术
11. 本刊对“通信作者”的要求. 中国医师杂志. 2020(04): 626 . 百度学术
12. 李强，付君静，窦文广，岳军艳，马栋. CT评价系统联合血浆D-二聚体对重症急性胰腺炎预后的预测价值. 中华实用诊断与治疗杂志. 2020(10): 1050-1053 . 百度学术
13. 张琳. 急性胰腺炎患者血浆D-二聚体变化与病情严重程度的相关分析. 中外医疗. 2019(32): 53-55 . 百度学术
其他类型引用(0)
计量
- 文章访问数: 394
- HTML全文浏览量: 16
- PDF下载量: 9
- 被引次数: 13
下载:
