Application Value of Dual-source Dual-energy CT Iodine Determination for Preoperative T Staging of Gastric Cancer
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摘要: 目的：研究并分析双源双能量CT碘值测定在胃癌术前T分期诊断中的价值。方法：选取2015年1月～2017年12月在我院进行双源双能量CT检查，且经手术病理证实为T分期的110例胃癌患者为研究对象，计算T1和T2-3期下动脉期和静脉期在胃壁内层、外层以及正常胃壁的标准化碘浓度（NIC），并40keV、60keV以及120keV时的图像质量客观指标和主观指标。结果：T分期下动、静脉期的胃壁内层与外层和正常胃壁碘基值均有统计学差异（P<0.05）。T分期下动静脉期的胃壁外层与正常胃壁的碘基值均无统计学差异（P>0.05）。120keV组的CT值、图像噪声、SNR及CNR图像质量客观指标均低于60keV组和40keV组（P<0.05）。60keV组的图像质量客观指标均低于40keV组（P<0.05）。60keV组的总体图像质量评分高于40keV组和120keV组（P<0.05）。三组在病灶显著性评分无统计学差异（P>0.05）。结论：采用双源双能量CT碘值测定方式，对于鉴别诊断T1和T2-3期胃癌具有显著价值，且能够提高图像的质量，对于增强胃癌术前T分期的准确率有重要意义。Abstract: To study and analyze the value of dual-source dual-energy CT iodine determination in preoperative T staging of gastric cancer. Methods: A total of 110 patients with gastric cancer who underwent dual-source dual-energy CT examination in our hospital from January 2015 to December 2017 and confirmed by surgical pathology were enrolled. The T1 and T2-3 phases were calculated. Normalized iodine concentration (NIC) in the inner and outer layers of the gastric wall and the normal stomach wall during arterial and venous phases, and objective and subjective indicators of image quality at 40keV, 60keV, and 120keV. Results: There was a statistically significant difference between the inner and outer layers of the gastric wall and the normal stomach wall in the T-stage of the lower and middle venous stages (P<0.05). There was no significant difference between the outer layer of the gastric wall and the normal stomach wall during the arteriovenous period (P>0.05). The objective values of CT value, image noise, SNR and CNR image quality in the 120keV group were lower than those in the 60keV group and the 40keV group (P<0.05). The objective quality indicators of the 60keV group were lower than the 40keV group (P<0.05). The overall image quality score of the 60keV group was higher than that of the 40keV group and the 120keV group (P<0.05). There were no significant differences in the significant scores of the three groups (P>0.05). Conclusion: The dual-source dual-energy CT iodine value method is of great value for the differential diagnosis of T1 and T2-3 gastric cancer, and can improve the image quality, which is of great significance for enhancing the accuracy of preoperative T staging of gastric cancer. Has a good clinical application value.
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Keywords:
- gastric cancer /
- T stage /
- dual source dual energy CT iodine
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期刊类型引用(12)
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