Abstract: Liver lesions are a common disease in our clinical work. Early intervention and accurate diagnosis are very important for treatment selection and improving the survival of patients. Spectrum CT, as new imaging technology, can provide single-energy imaging and multiple energy spectrum parameters for quantitative and qualitative evaluation of liver diseases, especially for highlighting the blood supply characteristics of liver diseases, which are contributed to the early detection, diagnosis and postoperative evaluation. This article reviews the application and research progress of spectral CT in those hypervascular liver lesions.