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基于两种AI软件对肺结节的诊断价值评价研究

陈新花 黄晓旗 李建龙 郭佑民

陈新花, 黄晓旗, 李建龙, 等. 基于两种AI软件对肺结节的诊断价值评价研究[J]. CT理论与应用研究, 2022, 32(0): 1-7. DOI: 10.15953/j.ctta.2022.087
引用本文: 陈新花, 黄晓旗, 李建龙, 等. 基于两种AI软件对肺结节的诊断价值评价研究[J]. CT理论与应用研究, 2022, 32(0): 1-7. DOI: 10.15953/j.ctta.2022.087
CHEN X H, HUANG X Q, LI J L, et al. Evaluation of diagnostic value of pulmonary nodules based on two AI softwares[J]. CT Theory and Applications, 2022, 32(0): 1-7. DOI: 10.15953/j.ctta.2022.087. (in Chinese)
Citation: CHEN X H, HUANG X Q, LI J L, et al. Evaluation of diagnostic value of pulmonary nodules based on two AI softwares[J]. CT Theory and Applications, 2022, 32(0): 1-7. DOI: 10.15953/j.ctta.2022.087. (in Chinese)

基于两种AI软件对肺结节的诊断价值评价研究

doi: 10.15953/j.ctta.2022.087
详细信息
    作者简介:

    陈新花:女,延安大学影像医学与核医学专业硕士研究生,主要从事胸部与骨关节影像诊断,Tel:15771808972,E-mail:523423054@qq.com

    李建龙:男,延安大学附属医院放射科主任医师,延安大学附属医院副教授、硕士生导师,主要从事胸部与骨关节影像诊断,Tel:13891163128,E-mail:yaljl116@163.com

    通讯作者:

    李建龙∗,

  • 中图分类号: R  814

Evaluation of Diagnostic Value of Pulmonary Nodules Based on Two AI Softwares

  • 摘要: 目的:探讨两种AI软件在≥5 mm肺结节中的临床应用价值。方法:选取2021年6月至2021年10月延安大学附属医院体检肺结节患者92例(共483个结节)。AI软件检测到的结节由影像学医师进行评估并记录其个数及结节类型;人工阅片由两名高年资影像学医师进行视觉评估,并以此作为识别结节的金标准。计算两个软件的检出率、假阳性率和假阴性率,评价两种AI软件的结节诊断价值。卡方检验和Fisher精确检验来比较不同软件与金标准之间的差异。最后,评价两种AI软件联合对肺结节的诊断价值。结果:软件A和软件B结节检出率为92.1% 和87.0%。软件A与人工阅片的吻合度一般(Kappa=0.213),软件B与人工阅片的吻合度较弱(Kappa=0.150)。软件A相比人工阅片对实性结节和钙化结节的检出有统计学差异;软件B相比人工阅片纯磨玻璃结节的检出有统计学差异。联合两种AI软件结节的检出率为97.1%,两种软件的联合与人工阅片比,结节类型的检出没有统计学差异。两种AI软件联合与人工阅片的吻合度较好(Kappa=0.439)。结论:两种AI软件联合会提高结节诊断及分类分析的能力。推荐联合诊断的方法用于临床,也为进一步提升AI软件数据集的同质化管理提供佐证。

     

  • 图  1  软件A肺结节识别界面

    Figure  1.  Pulmonary nodule recognition interface of software A

    图  2  软件B肺结节识别界面

    Figure  2.  Pulmonary nodule recognition interface of software B

    图  3  肺结节的不同类型

    Figure  3.  Different types of pulmonary nodules

    图  4  两种软件识别的假阳性结节

    Figure  4.  False positive nodules identified by two software

    图  5  两种软件识别的假阴性结节

    Figure  5.  False negative nodules identified by two software

    表  1  两种软件及两种软件联合对肺结节的检出情况

    Table  1.   Detection of pulmonary nodules by two kinds of software and their combination

    阅片方法 检出情况
    检出率/%假阳性率/%假阴性率/%
    软件A      92.13.527.87
    软件B      87.02.6913.0
    软件A联合软件B 97.11.042.91
    下载: 导出CSV

    表  2  两种AI软件及两种AI软件的联合对结节检出率的差异

    Table  2.   Difference of nodule detection rate between two artificial intelligence software and the combination of two artificial intelligence software

    软件 N(%)统计检验
    χ2PKappa
    软件A-人工阅片      445(92.1)25.5190.0000.213
    软件B-人工阅片      420(87.0)16.4720.0000.150
    软件A联合软件B-人工阅片 469(97.1)102.697 0.0000.439
    下载: 导出CSV

    表  3  两种AI软件对不同类型结节的检出情况

    Table  3.   Detection of different types of nodules by two artificial intelligence software

    变量 N结节检测软件P
    软件A(%)软件B(%)
    实性结节   295279(94.6)254(86.1)0.030
    部分实性结节  6 6(100.0) 3(50.0)0.000
    纯磨玻璃结节  68 56(82.4) 63(92.6)0.079
    钙化结节   114104(91.2)100(87.7)0.098
    下载: 导出CSV

    表  4  两种AI软件及两种AI软件联合识别不同类型结节的差异

    Table  4.   Differences of two artificial intelligence software and two artificial intelligence software in identifying different types of nodules

    变量实性结节部分实性结节纯磨玻璃结节钙化结节
    χ2Pχ2Pχ2Pχ2P
     软件A-人工阅片     10.693 0.0010.5380.0300.86214.8090.000
     软件B-人工阅片     0.8000.3710.1826.7410.0090.5560.456
     软件A联合软件B-人工阅片0.3810.5370.4640.2710.6030.0001.000
     注:-代表Fisher确切概率法没有相应的统计量。
    下载: 导出CSV
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出版历程
  • 收稿日期:  2022-05-18
  • 修回日期:  2022-09-28
  • 录用日期:  2022-09-29
  • 网络出版日期:  2022-10-25

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