新型冠状病毒感染的CT影像特点及演变规律

刘蓉辉; 何磊; 叶玉芳; 张淑倩; 陈英敏

doi:10.15953/j.ctta.2023.047

新型冠状病毒感染的CT影像特点及演变规律

doi: 10.15953/j.ctta.2023.047

河北省人民医院医学影像科, 石家庄050051

详细信息

通讯作者:
女，河北省人民医院医学影像科副主任医师、硕士研究生导师，主要从事呼吸系统疾病影像诊断，E-mail：ronghuiliu@163.com

中图分类号: R 814；R 563.1
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出版历程
- 收稿日期: 2023-03-12
- 修回日期: 2023-05-23
- 录用日期: 2023-05-29
- 网络出版日期: 2023-07-10
- 刊出日期: 2023-09-22

Characteristics and Evolution of Computed Tomography Images in Coronavirus Disease 2019 Pneumonia

Department of Medical Imaging, Hebei General Hospital, Shijiazhuang 050051, China

摘要

摘要: 目的：分析不同时期新型冠状病毒感染的CT影像特点及演变规律。方法：回顾性分析2022年12月至2023年1月期间113例河北省人民医院确诊COVID-19患者不同时期的CT征象，观察其变化趋势。32例患者行1次CT检查，41例行CT检查2次，20例行CT检查3次，15例行CT检查4次，5例行CT检查5次。本组113例患者共行CT检查259次。其中早期（新冠感染 7 d以内）32例患者CT检查32次，进展期（新冠感染8～30 d）74例患者CT检查87次，转归期（新冠感染12～57 d）89例患者CT检查140次。分析患者每次CT特点。结果：早期CT表现为磨玻璃密度影26次，实变+磨玻璃密度影 6次。进展期磨玻璃密度影32次，实变+磨玻璃密度影 55次。转归期48次磨玻璃密度影，90次实变+磨玻璃密度影。112例患者为多叶多发病灶，其中1例在转归期为单叶多发病灶。早期胸膜下分布13次，支气管血管束周围+胸膜下分布 19次。进展期胸膜下分布24次，支气管血管束周围+胸膜下分布 63次。转归期胸膜下分布48次，2次完全吸收好转，支气管血管束周围+胸膜下分布 90次。早期磨玻璃密度影内小叶间隔增粗32次，病灶内血管增粗32次。进展期病灶内小叶间隔增粗85次，病灶内血管增粗87次。转归期小叶间隔增粗5次，病灶内血管增粗1次，48次伴条索影。早期1次支气管气充气征，进展期6次胸腔积液，6次支气管充气征，3次肺气肿，转归期2次支气管充气征，1次胸腔积液。结论：不同时期新冠肺炎患者的CT影像特点有所差别，了解其演变规律对指导临床治疗至关重要。
- CT /
- 新型冠状病毒肺炎 /
- 影像特点 /
- 变化趋势
Abstract: Objective: To analyze the computed tomography (CT) imaging features and evolution of different stages of coronavirus disease 2019 (COVID-19). Methods: A retrospective analysis was conducted on the CT images of 113 patients diagnosed with COVID-19 at Hebei Provincial People's Hospital between December 2022 and January 2023 to observe the trends of imaging changes. Results: All 113 patients were clinically diagnosed with COVID-19. Among these, 32, 41, 20, 15, and five patients underwent CT examination once, twice, three times, four times, and five times, respectively. A total of 259 CT examinations were performed in this group of 113 patients. Among them, 32 were early-stage (within 7 days of COVID-19 infection) examinations, 87 were progression-stage CT examinations, and 140 were recovery-stage CT examinations. Analysis of the imaging features of each CT examination of the patients was performed to identify the imaging features and evolution rules of COVID-19. Among the 32 examinations performed in 32patients with early-stage disease (within 7 days of COVID-19 infection), 26 cases showed ground-glass density shadows and six cases additionally showed solid nodules. In the progression stage (8 ~ 30 days after COVID-19 infection), among the 87 CT examinations in 74 patients, 62, 11, and one patient underwent examinations one, two, and three times, respectively. The 87 examinations revealed there 32 cases with ground-glass density shadows and 55 cases with additional solid nodules. In the recovery stage (12 ~ 57 days after COVID-19 infection), 89 patients underwent 140 CT examinations. Among these, 48, 32, eight, and one patient underwent CT examinations once, twice, three times, and four times, respectively. Among the 140 CT examinations, 48 cases showed ground-glass density shadows, while 90 cases additionally showed solid nodules. Moreover, 112 patients had multiple lesions in multiple lobes, with only one case having multiple lesions in a single lobe. Regarding the distributions, in the early stage, 13 cases had subpleural distributions and 19 cases had peribronchovascular and subpleural distributions. In the progression stage, 24 cases had subpleural distribution, and 63 cases had peribronchovascular and subpleural distributions. In the recovery stage, 48 cases had subpleural distribution, two cases showed complete absorption and improvement, and 90 cases had peribronchovascular and subpleural distribution, with 48 cases accompanied by reticular shadows. Regarding thickening of the interlobular septa and vessels within the lesions, in the early stage, 32 cases showed thickening of the interlobular septa and vessels within the lesions. In the progression stage, 85 cases showed thickening of the interlobular septa and 87 cases showed thickening of vessels within the lesions. In the recovery stage, five cases showed thickening of the interlobular septa, one case showed thickening of vessels within the lesions, and 48 cases were accompanied by linear shadows. Finally, in the early stage, one case showed bronchial gas inflation. In the progression stage, six cases showed pleural effusion, six cases showed bronchial inflation, and three cases showed pulmonary emphysema. In the recovery stage, two cases showed bronchial inflation and one case showed pleural effusion. Conclusion: The characteristics of CT images differed in patients with new coronary pneumonia at different times. Understanding this evolution is important to guide clinical treatment.
- CT /
- novel coronavirus pneumonia /
- image characteristics /
- changing trends

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图 1 新冠肺炎不同时期CT表现

Figure 1. CT imaging features and evolution of different stages of COVID-19

下载: 全尺寸图片幻灯片

表 1 不同时期CT表现

Table 1. CT findings in patients with new coronary pneumonia in different periods

CT表现	早期	进展期	转归期
磨玻璃	26（81％）	32（37％）	48（34％）
实变+磨玻璃	6（19％）	55（63％）	90（64％）
胸膜下分布	13（40％）	24（28％）	48（34％）
胸膜下+支气管血管周围分布	19（60％）	63（72％）	90（64％）
多叶	32（100％）	87（100％）	137（98％）
单叶			1（2％）
其内小叶间隔增粗	32（100％）	85（97％）	5（3％）
其内血管增粗	32（100％）	87（100％）	1（10％）
支气管充气征	1（3％）	6（7％）	2（1％）
条索		48（55％）	48（34％）
胸腔积液		6（7％）	1（1％）
肺气肿		3（3％）

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