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佛山市成年居民骨密度CT定量研究

吴伟智 方挺松 梁振华 祝翠玲 周静仪

吴伟智, 方挺松, 梁振华, 等. 佛山市成年居民骨密度CT定量研究[J]. CT理论与应用研究, 2023, 32(0): 1-8. DOI: 10.15953/j.ctta.2023.098
引用本文: 吴伟智, 方挺松, 梁振华, 等. 佛山市成年居民骨密度CT定量研究[J]. CT理论与应用研究, 2023, 32(0): 1-8. DOI: 10.15953/j.ctta.2023.098
WU W Z, FANG T S, LIANG Z H, et al. Quantitative CT Study of Bone Mineral Density for Adults Residents in Foshan[J]. CT Theory and Applications, 2023, 32(0): 1-8. DOI: 10.15953/j.ctta.2023.098. (in Chinese)
Citation: WU W Z, FANG T S, LIANG Z H, et al. Quantitative CT Study of Bone Mineral Density for Adults Residents in Foshan[J]. CT Theory and Applications, 2023, 32(0): 1-8. DOI: 10.15953/j.ctta.2023.098. (in Chinese)

佛山市成年居民骨密度CT定量研究

doi: 10.15953/j.ctta.2023.098
基金项目: 2022年佛山市自筹经费类科技创新项目入库培育项目(2220001004568);佛山市“十四五”医学重点专科项目(FSZD145011)。
详细信息
    通讯作者:

    男,硕士,佛山市中医院放射科副主任医师,主要研究方向为骨关节系统疾病的影像诊断与人工智能影像组学,E-mail:success2@163.com

Quantitative CT Study of Bone Mineral Density for Adults Residents in Foshan

  • 摘要: 目的:研究佛山地区成年人椎体骨密度(BMD)与性别、年龄的关系,探讨本地区不同年龄段BMD均值及各年龄段骨质疏松症(OP)的发病率。方法:对佛山市中医院2021年10月至2023年3月的1065例(男性648例,女性417例)健康成年人体检者使用定量C(QCT)行椎体BMD检测,按年龄段进行分组,采用t检验和方差分析对不同性别、不同年龄段BMD值进行检验,采用$\chi^2 $检验和相关分析对不同性别、不同年龄段的OP发病率进行分析。结果:20~29岁、30~39岁、40~49岁及60~69岁、70~79岁不同性别间的BMD差异均有统计学意义(P<0.05),女性BMD在青中年时期高于男性。在40~49岁、50~59岁、60~69岁、70~79岁男性组及30~39、40~49岁、50~59岁、60~69岁女性组中,同性别不同年龄段间的BMD值差异有统计学意义(P<0.05),且随年龄的增长呈下降趋势;同性别不同年龄段的OP发病率差异均有统计学意义(P<0.05),年龄与OP发病率呈正相关关系(r=0.517,r=0.636)。结论:佛山市健康成年人QCT测量的椎体BMD与性别、年龄相关,在20~29岁达到峰值,随年龄的增长而下降;从40~49岁开始,OP发病率在男性和女性中随着年龄的增长而增加。

     

  • 图  1  椎体骨密度QCT测量方法

    QCT测量的是椎体中央骨松质的体积骨密度,兴趣区避开骨皮质、骨岛和椎体后静脉区;其测量结果不受身高体重、脊柱侧弯、退变和血管钙化等因素的影响。

    Figure  1.  Measurement of vertebral bone mineral density by QCT

    表  1  1065例健康成年人胸部CT体检者椎体BMD分析($\bar x \pm s $,mg/cm3

    Table  1.   Analysis of vertebral BMD in 1065 healthy adults undergoing chest CT examination

    年龄组/岁男性女性tP
    人数/例BMD人数/例BMD
    20~2941163.31±26.2821188.38±28.79-3.4420.001
    30~3993160.62±26.8664172.42±29.21b-2.610.01
    40~49168145.47±29.67a97158.05±32.5b-3.2110.001
    50~59211127.1±28.72a127127.95±38.05b-0.2150.83
    60~6979107.54±29.85a6792.36±25.64 b3.2630.001
    70~794096.11±23.6a2584.43±18.112.1140.038
    80~891691.51±26.781677.38±17.211.7750.086
    F56.89374.37
    P<0.001 <0.001
    注:a表示在男性组中,该年龄段与前一年龄段比较P<0.05;b表示在女性组中,该年龄段与前一年龄段比较P<0.05。
    下载: 导出CSV

    表  2  1065例健康成年人胸部CT体检者骨质疏松筛查结果[例(%)]

    Table  2.   Screening results of osteoporosis in 1065 healthy adults undergoing chest CT examination

    年龄组/岁男性女性
    正常低骨量OP严重OP正常低骨量OP严重OP
    20~2938(92.68)3(7.32)0(0)0(0)21(100)0(0)0(0)0(0)
    30~3990(96.77)3(3.23)0(0)0(0)61(95.31)3(4.69)0(0)0(0)
    40~49137(81.55)29(17.26)1(0.6)1(0.6)85(87.63)11(11.34)0(0)1(1.03)
    50~59125(59.24)68(32.23)13(6.16)5(2.37)68(53.54)41(32.28)12(9.45)6(4.72)
    60~6925(31.65)39(49.37)13(16.46)2(2.53)8(11.94)35(52.24)22(32.84)2(2.99)
    70~794(10)23(57.50)11(27.50)2(5)1(4)11(44)10(40)3(12)
    80~892(12.5)7(43.75)4(25)3(18.75)0(0)4(25)10(62.5)2(12.5)
    $\chi^2 $225.201235.748
    P<0.001<0.001
    下载: 导出CSV
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