ISSN 1004-4140
CN 11-3017/P
李建军, 刘艳东, 李新彤, 等. 中老年髋部骨折患者肌肉脂肪与年龄及体质指数的相关性[J]. CT理论与应用研究(中英文), xxxx, x(x): 1-7. DOI: 10.15953/j.ctta.2023.143.
引用本文: 李建军, 刘艳东, 李新彤, 等. 中老年髋部骨折患者肌肉脂肪与年龄及体质指数的相关性[J]. CT理论与应用研究(中英文), xxxx, x(x): 1-7. DOI: 10.15953/j.ctta.2023.143.
LI J J, LIU Y D, LI X T, et al. Correlations of Hip Muscle Composition with Age and Body Mass Index in Middle-aged and Elderly Patients with Hip Fracture[J]. CT Theory and Applications, xxxx, x(x): 1-7. DOI: 10.15953/j.ctta.2023.143. (in Chinese).
Citation: LI J J, LIU Y D, LI X T, et al. Correlations of Hip Muscle Composition with Age and Body Mass Index in Middle-aged and Elderly Patients with Hip Fracture[J]. CT Theory and Applications, xxxx, x(x): 1-7. DOI: 10.15953/j.ctta.2023.143. (in Chinese).

中老年髋部骨折患者肌肉脂肪与年龄及体质指数的相关性

Correlations of Hip Muscle Composition with Age and Body Mass Index in Middle-aged and Elderly Patients with Hip Fracture

  • 摘要: 目的:探讨中老年髋部骨折患者的髋部肌肉脂肪与年龄、体质指数(BMI)的相关性。方法:回顾性收集175例51~95岁的低能量髋部骨折患者的髋部CT图像,其中男性56例,年龄(75.0±12.1)岁,女性119例,年龄(78.0±9.7)岁,并根据年龄分为<80岁组和≥80岁组。使用定量CT获得患者健侧髋部的肌肉横截面积(CSMA)、总脂肪面积(TAA)、肌肉间隙内脂肪面积(IMAA)、皮下脂肪面积(SAA)及肌肉脂肪浸润程度(MFI)。使用独立样本t检验比较不同性别、不同年龄组之间的差异,并使用偏相关分析髋部肌肉脂肪面积与年龄及BMI的相关性。结果:中老年男性髋部的TAA、SAA、MFI明显低于女性,CSMA明显高于女性。男性及女性<80岁组的CSMA均高于≥80岁组,MFI均低于≥80岁组。控制BMI因素,中老年男性、女性的年龄均与IMAA、MFI呈正相关(男r=0.445、0.612,女r=0.202、0.390),与CSMA呈负相关(男r=-0.673,女r=-0.428)。控制年龄因素,中老年男性的BMI与TAA、IMAA、SAA及CSMA呈正相关(r=0.430、0.491、0.389、0.623),中老年女性的BMI与TAA、IMAA、SAA、CSMA及MFI均呈正相关(r=0.510、0.389、0.478、0.295、0.296)。结论:在中老年髋部脆性骨折患者中,男性肌肉更多,总脂肪更少,但肌间脂肪与女性相仿;年龄越大,肌肉越小,肌间脂肪越多;BMI越大,肌肉和脂肪越多,但男性的MFI与BMI无关。

     

    Abstract: Objective: To investigate the correlations of hip muscle composition with age and body mass index (BMI) in middle-aged and elderly patients with hip fracture. Methods: In total of 175 patients aged 51~95 years with low-energy hip fracture who underwent hip computed tomography scans were divided into <80 and ≥80 year-old groups. Quantitative computed tomography (QCT) was performed to obtain the cross-sectional muscle area (CSMA), total adipose area (TAA), intra-muscular adipose area (IMAA), subcutaneous adipose area (SAA) and muscle fat infiltration (MFI) of the hip. An independent t-test was used to compare the differences between gender and groups, and correlation analysis was used to determine the relationships between hip muscle fat area and age and BMI. Results: The hip TAA, SAA and MFI of men were significantly lower than those of women (t=−2.356, −2.550, −3.090), and CSMA was significantly higher than that of women. The CSMA in the <80 year-old age group was higher than that of the ≥80 year-old age group, and the MFI was lower than that found in the ≥80 years age old group. After adjusting for BMI, the age of men and women positively correlated with IMAA and MFI (r=0.445 and 0.612 for men, r=0.202 and 0.390 for women), and negatively correlated with CSMA (r=−0.673 for men, r=−0.428 for women). After adjusting for age, the BMI of men positively correlated with TAA, IMAA, SAA, and CSMA (r=0.430, 0.491, 0.389, 0.623), whereas the BMI of women positively correlated with TAA, IMAA, SAA, CSMA, and MFI (r=0.510, 0.389, 0.478, 0.295, 0.296). Conclusion: In middle-aged and elderly patients with hip fragility fractures, men had more muscle and less total fat than those in women, but similar intermuscular fat to that of women. Hip muscle mass decreased and intermuscular fat increased with age. Generally, higher BMI, correlated with more muscle and fat. However, MFI in men was not associated with BMI.

     

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