Abstract: Ovarian cystadenofibroma (OCAF) is a rare ovarian tumor of epithelial origin and is composed of Mullerian epithelium and fibrous stromal cells on the surface of the ovary. Its clinical incidence is rare, and serous is the most common. This article reports a case of ovarian seromucinous cystadenofibroma in a 76-year-old female who presented abdominal pain for more than two years and a palpable mass in the lower abdomen for eight months. MRI shows the lesions are cysts of varying sizes with heterogeneous signals,and they demonstrate markedly hypointense signals on T2WI. Imaging diagnosis of cystadenofibroma is performed. The postoperative pathological diagnosis was seromucinous cystadenofibroma, and the patient achieved favorable follow-up outcomes. This article aims to provide an imaging description and summary of the disease to improve its diagnosis accuracy.