摘要:
评价支气管动脉灌注化疗栓塞及CT导引下注入无水乙醇与超液化碘油双介入疗法治疗原发性肺癌的疗效。材料和方法:20例原发肺癌进行了单纯支气管动脉化疗,累计68次;20例进行了单纯支气管动脉化疗栓塞;另外40例均进行了双介入治疗,其中20例在支气管动脉化疗栓塞的同时进行了CT导引下注射无水乙醇与超液化碘油混合剂的介入治疗(PEI),化疗栓塞共计28次, 局部化疗40次。单纯化疗合并CT介入治疗20例,化疗共64次,以上40例进行的CT导引下注射无水乙醇与超液化碘油混合剂的介入治疗次数累计118次。结果:采用支气管动脉化疗栓塞(或化疗)合并 CT导引下注射无水乙醇的双介入疗法治疗有效率分别为 90%和80%,单纯支气管动脉化疗栓塞及单纯化疗的临床有效率分别为 70%和30%,双介入与单介入的有效率比较有显著性差异 (P<0.01)。随访双介入疗法治疗后的患者,3年生存率达到50%。结论:双介入疗法较单纯支气管动脉化疗或化疗栓塞治疗肺癌的临床有效率、生存率明显提高。
Abstract:
Purpose: To analyse and evaluate the therapeutic effect of the double interventional therapy of bronchial artery chemotherapy and CT guided percutaneous absolute alcohol injection (PEI) in primary lung carcinoma. Meterials and Methods: 20 cases with primary lung carcinoma were treated by single bronchial artery chemotherapy, the total times were 68; 20 cases were treated by single chemoembolism, the total times were 22; 40 cases were all treated by double interventional therapy in the same time of chemotherapy, 20 cases were treated by bronchial artery embolism, the total operations were 28 times, and the local chemotherapy was 40 times. Single chemotherapy were 20 cases, it was total 64 times. During the period of treatment, CT guided percutaneous absolute alcohol injection therapy was done on the 40 patients, it was total 118 times. ResultS: The clinic effective rates of bronchial artery chemoembolism and single chemotherapy were 70% and 30%. The clinic effective rate of double intervention therapy is 90% and 80% individually. No adverse reaction and severe complications occurred. Conclusion: Double interventional therapy has much higher clinic effective rates and survival rate than single bronchial artery chemotherapy or chemo embolism. It has notable difference (P＜0.01).
下载:
