Abstract: Objective: To evaluate the value of the dual source CT air enema intestinal examination in the diagnosis of small bowel diseases.Methods: 15 patients with suspected small bowel diseases underwent dual-source CT inspection before or after the capsule endoscopy within 3 days.Among them,8 males and 7 females,the oldest 42 years old,the youngest 23 years old.The major symptoms were abdominal pain in 10 cases,blood and pus stool in 4 cases,1 case of unexplained weight loss,the longest duration was 4 years and the shortest was 1 month.Results: Capsule endoscopy showed normal in 8 cases,dual-source CT examination were no exception.Dual-source CT diagnosed Crohn diseases in 4 cases,clinical diagnosis with capsule endoscopy were the same.Capsule endoscopy suspected tumors in 3 cases,but dual-source CT examination only found two positive cases,with diagnosis of benign and malignant,of which,confirmed by pathology,1 was jejunum stromal tumors,another was ileal adenocarcinoma.Only one case with 3cm size was suspected the tumor in capsule endoscopy,but in dual source CT was normal.Combined with MRI,and clinical history,the issue was proved to be false positive.Conclusion Dual source CT air enema intestinal examination could not only show the scope of the relationship with adjacent structures,and identify clinical inflammation and cancer lesions,and make the tumor differentiation of benign and malignant lesions.The examinations are also valuable for capsule endoscopy to confirm localization and scope of lesions,and rule out false positive.