ISSN 1004-4140
CN 11-3017/P
Hengyong Yu, Qiong Xu, Peng He, James Bennett, Raja Amir, Bruce Dobbs, 牟轩沁, 魏彪, Anthony Butler, Phillip Butler, Ge Wang. 基于Medipix的谱微CT[J]. CT理论与应用研究, 2012, 21(4): 583-596.
引用本文: Hengyong Yu, Qiong Xu, Peng He, James Bennett, Raja Amir, Bruce Dobbs, 牟轩沁, 魏彪, Anthony Butler, Phillip Butler, Ge Wang. 基于Medipix的谱微CT[J]. CT理论与应用研究, 2012, 21(4): 583-596.
Hengyong Yu, Qiong Xu, Peng He, James Bennett, Raja Amir, Bruce Dobbs, MOU Xuan-qin, WEI Biao, Anthony Butler, Phillip Butler, Ge Wang. Medipix-based Spectral Micro-CT[J]. CT Theory and Applications, 2012, 21(4): 583-596.
Citation: Hengyong Yu, Qiong Xu, Peng He, James Bennett, Raja Amir, Bruce Dobbs, MOU Xuan-qin, WEI Biao, Anthony Butler, Phillip Butler, Ge Wang. Medipix-based Spectral Micro-CT[J]. CT Theory and Applications, 2012, 21(4): 583-596.

基于Medipix的谱微CT

基金项目: 

supported in part by NIH/NIBIB grant EB011785,the Ministry of Science and Innovation(New Zealand),a seed grant from Wake Forest Institute for Regenerative Medicine

详细信息
    作者简介:

    Hengyong Yu received his Bachelor degrees in information science & technology (1998) and computational mathematics (1998), and his PhD in information & telecommunication engineering (2003) from Xi’an Jiaotong University. He was Associate Research Scientist with the University of Iowa (2004~2006), and Research Scientist with Virginia Tech (2006~2010). Since 2010, he has been an Assistant Professor, the Director of CT Lab, Departments of Radiology and Biomedical Engineering, Wake Forest University Health Sciences. His interests include computed tomography and medical image processing. He has authored or coauthored>90 peer-reviewed journal papers. He is a senior member of the Institute of Electrical and Electronics Engineers (IEEE) and the IEEE Engineering in Medicine and Biology Society (EMBS), and member of the American Association of Physicists in Medicine (AAPM) and the Biomedical Engineering Society (BMES). In 2012, he received an NSF CAREER award for the development of compressive sensing based interior tomography.

  • 中图分类号: TP391.41

Medipix-based Spectral Micro-CT

Funds: 

supported in part by NIH/NIBIB grant EB011785,the Ministry of Science and Innovation(New Zealand),a seed grant from Wake Forest Institute for Regenerative Medicine

  • 摘要: 自从几十年前豪斯菲尔德因其突破性工作而赢得诺贝尔奖以来,X线CT已经被广泛的应用到了临床前以及临床应用,并产生了海量的灰度断层图像。由于其固有的光子计数问题涉及到较高的辐射剂量,这些灰度断层图像的软组织对比度差,经常难以提供一些关键性的细节而满足诊断的需要。从物理的角度来看,X线的谱是多能的,获得多能CT(亦被称为谱CT,真彩色CT)图像是可行的。这种谱图像提供了强有力的新诊断信息。近年来,新兴的Medipix技术提供了一种准确而快速的高分辨率能量选择的X线检测技术。本文将以我们小组的研究结果为重点来综述基于Medipix的谱微CT的研究进展。主要内容包括:先进的MediPix检测器,商业化MARS谱微CT的系统与方法,以及混合谱微CT的设计以及彩色扩散现象。
    Abstract: Since Hounsfield's Nobel Prize winning breakthrough decades ago, X-ray CT has been widely applied in the clinical and preclinical applications-producing a huge number of tomographic gray-scale images. However, these images are often insufficient to distinguish crucial differences needed for diagnosis. They have poor soft tissue contrast due to inherent photon-count issues, involving high radiation dose. By physics, the X-ray spectrum is polychromatic, and it is now feasible to obtain multi-energy, spectral, or true-color, CT images. Such spectral images promise powerful new diagnostic information. The emerging Medipix technology promises energy-sensitive, high-resolution, accurate and rapid X-ray detection. In this paper, we will review the recent progress of Medipix-based spectral micro-CT with the emphasis on the results obtained by our team. It includes the state-of-the-art Medipix detector, the system and method of a commercial MARS (Medipix All Resolution System) spectral micro-CT, and the design and color diffusion of a hybrid spectral micro-CT.
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出版历程
  • 收稿日期:  2012-06-07
  • 网络出版日期:  2022-12-12

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