摘要:
目的:通过分析颈总-颈内动脉粥样硬化斑块性质及管腔狭窄程度评估和预测冠状动脉性心脏病(CAD)的发生与发展。方法:回顾性分析81例患者的头颈部CTA和冠状动脉CTA资料,评估图像质量和动脉粥样硬化斑块的性质,并计算狭窄程度。按照颈总-颈内动脉狭窄程度可分为两组:中度及以上狭窄组和轻度狭窄组,对相应冠状动脉管腔狭窄程度分别做两组间独立样本t检验。并按行头颈部CTA检查患者头颅CT平扫结果进行分组:脑梗死组和无脑梗死组,并进行两组间t检验。按颈总-颈内动脉中度及以上狭窄组和轻度狭窄组短暂性脑缺血发作(TIA)的发生概率作χ2检验。分析81例患者静态心电图、心绞痛以及TIA发生率与有无脑梗死以及颈总-颈内动脉狭窄程度之间的相关性。结果:81例患者中,脑梗死组和无脑梗死组冠状动脉斑块形成处狭窄程度t检验结果有显著统计学差异(P<0.05),即脑梗死组相应冠状动脉狭窄程度较非脑梗死组重。经配对χ2检验,颈总-颈内动脉狭窄程度影响TIA的发生概率(P<0.05)。对81例患者分析其静态心电图,有TIA组静态心电图ST-T段改变以及心绞痛发生率明显高于无TIA组(P<0.05)。结论:颈总-颈内动脉狭窄程度与相应冠状动脉粥样硬化病变的发展存在关联。冠状动脉狭窄程度与脑梗死及相应颈总-颈内动脉狭窄程度有关。颈总-颈内动脉存在中度及以上狭窄时,TIA的发生率增加,且TIA组受检者静态心电图ST-T段改变以及心绞痛发生率均高于无TIA组。
Abstract:
Objective: To evaluate and forecast the occurrence of obstructive coronary artery disease (CAD) and development through carotid artery atherosclerotic plaque and luminal stenosis degree. Methods: 81 patients who had exarned both with head-and-neck CTA and coronary CTA were retrospectively analyzed, evaluating image quality and the nature of the atherosclerotic plaque, and calculate the degree of stenosis. According to the carotid artery stenosis degree can be divided into two groups: moderate or more narrow and mild stenosis group, and the corresponding coronary artery luminal stenosis degree for independent samples t test between the two groups respectively. Line and according to the patients with head and neck CTA inspection head CT scan results grouping: cerebral infarction group and cerebral infarction, and t test between the two groups. According to the common carotid, internal carotid artery level is above moderate stenosis group and mild stenosis group transient ischemic attack (TIA) of the probability for a chi-square test. Static analysis of 81 cases of patients ECG, angina pectoris, and transient ischemic attack incidence and presence of cerebral infarction and carotid-the relationship between the degree of internal carotid artery stenosis. Results: in 81 cases of simultaneously or successively in the patients with head and neck CTA and coronary CTA, head CT scan of cerebral infarction, coronary artery plaque formation corresponding degree of stenosis, the t test results between the two groups have statistically significant difference (P< 0.05). The corresponding degree of coronary artery stenosis cerebral infarction group than in cerebral infarction group, t test results between the two groups have statistically significant differences (P < 0.05). Of common carotid, internal carotid artery stenosis degree of TIA probability of McNemar test have a statistically significant difference (P < 0.05). In 81 cases with analysis of its static ECG, TIA set of static electrocardiogram ST-T change and rate of angina pectoris occurred was obviously higher than that of the TIA group (P<0.05).Conclusion: carotid, internal carotid artery stenosis degree and the development of coronary atherosclerosis lesions corresponding correlation. There was a moderate or above internal carotid artery stenosis, the incidence of TIA, and the TIA group client static ECG ST-T period of change and the incidence of angina pectoris were higher than without the TIA group.
百度学术
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