A Preliminary Study of Correlation between Dynamic Contrast Enhancement MRI and ¹⁸F-FDG PET/CT in Small Peripheral Lung Cancer

Objective: To investigate the correlations of the dynamic contrast enhancement MRI (DCE-MRI) and glucose metabolism determined by the maximum standardized uptake value (SUV_max) at ¹⁸F-FDG PET/CT in small peripheral cell lung cancer. Methods: ¹⁸F-FDG PET/CT and DCE-MRI wereperformed in 27 consecutive patients with histologically verifiedsmall peripherallung cancer (maximal diameter ≤ 3 cm). The quantitative MR pharmaeokineticparameters including K^trans, K_ep, V_e and SUV_max were measured. Pearson's correlations were conducted between the three MR parameters and SUV_max.Results: Positive correlations were found between K^trans and SUV max, K_ep and SUV_max (P < 0.05). No significant correlation was found for thecomparison of V_e and SUV max (P>0.05). Conclusions: Positive correlationswere found between K^trans and SUV_max, K_ep and SUV_max. Combination of three parameters can reflect the malignant feature of lung cancer.