ISSN 1004-4140
CN 11-3017/P
LIU Li, JIN Mei, LI Xin, YAN Xiaoguang, CHEN Tong, KANG Xin, CHEN Wenjing, GAO Xiaolong. Research on the Correlation between Diagnostic Efficacy and Pathological Type of Dual-energy CT in Thyroid Nodules[J]. CT Theory and Applications, 2021, 30(5): 611-618. DOI: 10.15953/j.1004-4140.2021.30.05.09
Citation: LIU Li, JIN Mei, LI Xin, YAN Xiaoguang, CHEN Tong, KANG Xin, CHEN Wenjing, GAO Xiaolong. Research on the Correlation between Diagnostic Efficacy and Pathological Type of Dual-energy CT in Thyroid Nodules[J]. CT Theory and Applications, 2021, 30(5): 611-618. DOI: 10.15953/j.1004-4140.2021.30.05.09

Research on the Correlation between Diagnostic Efficacy and Pathological Type of Dual-energy CT in Thyroid Nodules

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  • Received Date: May 20, 2021
  • Available Online: September 22, 2021
  • Objective: We intended to explore the correlation between diagnostic efficacy and histopathological types when dual-energy CT was applied in thyroid nodules, aiming to improve the accuracy of clinical diagnosis of thyroid cancer. Methods: We selected 224 patients with thyroid nodules diagnosed and treated by head and neck surgery in our hospital from January 2018 to October 2020. 148 cases with thyroid cancer formed observation group while 76 cases with benign thyroid nodules formed contrast group, then the preoperative CT manifestations were analyzed and compared with postoperative pathological results. Results: Among the 224 patients with thyroid nodules(148 cases with thyroid cancer formed the observation group while 76 cases with benign nodules formed the contrast group), 102 cases showed irregular nodules, 104 cases showed "peninsular" nodules, 106 nodules showed "enhanced remnant" signs, 89 cases showed "sand-lik" calcification and 84 cases with malignant nodules showed tumor invasion on surrounding tissues and organs. The ratio of standard iodine concentration and the slope of energy spectrum curve of benign thyroid nodules in arteriovenous stage were higher than those in malignant nodule group. We found significant differences between the two groups. Conclusion: The quantitative analysis of dual energy CT combined with CT signs hold certain characteristics for thyroid cancer discriminations. Different pathological types are closely related with iodine map and energy spectrum curve, which can lead to correct preoperative diagnosis and provide imaging basis for clinical diagnosis and treatment.
  • [1]
    沈莎莎. 基于甲状腺癌灶CT影像组学模型预测中央组淋巴结转移的可行性研究[D]. 昆明:昆明医科大学, 2019, 21(9):567-578.
    [2]
    张波, 康凯夫, 岳振营. 间变性甲状腺癌的临床病理特征、分子病理学研究及治疗展望[J]. 诊断病理学杂志, 2020, 27(10):754-758.
    [3]
    潘冬梅, 李正腾, 王敏, 等. 双源CT双能量扫描测定甲状腺碘浓度、体积及总碘含量的价值[J]. 医学影像学杂志, 2020, 30(3):409-412.

    PAN D M, LI Z T, WANG M, et al. Dual-source CT dual-energy scanning in measuring iodine concentration, volume and total iodine of normal thyroid tissue[J]. Journal of Medical Imaging, 2020, 30(3):409-412. (in Chinese).
    [4]
    何慕真. 双源能谱CT成像在术前诊断甲状腺乳头状癌颈部淋巴结转移的应用价值[D]. 福州:福建医科大学, 2017.
    [5]
    罗雯, 傅颖. ECT联合B超、CT检查对甲状腺癌诊断的临床价值[J]. 中南医学科学杂志, 2020, 48(5):509-512.

    LUO W, FU Y. The clinical value of ECT combined with B ultrasound and CT in the diagnosis of thyroid cancer[J]. Medical Science Journal of Central South China, 2020, 48(5):509-512. (in Chinese).
    [6]
    何俊林, 王永胜, 蔡剑波, 等. 甲状腺结节CT征象分析及诊断价值研究[J]. 医药论坛杂志, 2018, 39(7):17-20.

    HE J L, WANG Y S, CAI J B, et al. Study on CT signs of thyroid nodules and their diagnostic value[J]. Journal of Medical Forum, 2018, 39(7):17-20. (in Chinese).
    [7]
    SOLODYANNIKOVA O I, KMETYUK Y V, DANILENKO V V, et al. Radioisotope diagnostic algorithm for the relapse and metastases detection in the iodine-negative differentiated thyroid cancer[J]. Problemy Radiatsiinoi Medytsyny ta Radiobiolohii, 2020, 25:579-591.
    [8]
    XING Z C, QIU Y X, YANG Q R, et al. Thyroid cancer neck lymph nodes metastasis:Meta-analysis of US and CT diagnosis[J]. European Journal of Radiology, 2020, 109103.
    [9]
    SAMARASINGHE S, YUKSEL S, MEHROTRA S. Intermixed medullary and papillary thyroid cancer in a patient with renal cell carcinoma[J]. Endocrinology, Diabetes & Metabolism Case Reports, 2020:20-0025. DOI: 10.1530/EDM-20-0025.
    [10]
    MADHOK J, KLOOSTERBOER A, VENKATASUBRAMANIAN C, et al. Catecholamine-induced cerebral vasospasm and multifocal infarctions in pheochromocytoma[J]. Endocrinology, Diabetes & Metabolism Case Reports, 2020:20-0078. DOI: 10.1530/EDM-20-0078.
    [11]
    李琳. 能谱CT在甲状腺病变诊断及鉴别诊断中的应用研究[D]. 北京:北京协和医学院, 2017.
    [12]
    MELTZER D E, PARNES B, CHAI R. Papillary thyroid carcinoma metastasis to the pituitary:A case report[J]. Clinical Imaging, 2021, 74:41-44.
    [13]
    YEOM J A, ROH J, JEONG Y J, et al. Ultra-low-dose neck CT with low-dose contrast material for preoperative staging of thyroid cancer:Image quality and diagnostic performance[J]. American Journal of Roentgenology, 2018, 212(4):1-6.
    [14]
    王艳霞, 杨守京. 梭形细胞型髓样甲状腺癌四例临床病理学特征[J]. 中华病理学杂志, 2020, 49(8):839-841.

    WANG Y X, YANG S J. Spindle cell variant of medullary thyroid carcinoma:a clinicopathological analysis of 4 cases[J]. Chinese Journal of Pathology, 2020, 49(8):839-841. (in Chinese).
    [15]
    徐娜, 李军, 孟庆涛, 等. 螺旋CT扫描对甲状腺癌临床诊断与治疗的应用价值[J]. 中国CT和MRI杂志, 2021, 19(1):59-75.

    XU N, LI J, MENG J T, et al. Application Value of Spiral CT in Clinical Diagnosis and Treatment of Thyroid Carcinoma[J]. China CT and MRI Magazine, 2021, 19(1):59-75. (in Chinese).
    [16]
    ZHU Y C, ALZOUBI A, JASSIM S, et al. A generic deep learning framework to classify thyroid and breast lesions in ultrasound images[J]. Ultrasonics, 2021, 110:106300.
    [17]
    YE K L, KUANG Y Y, LIANG J Y, et al. Diagnostic value of Dual-energy CT in differentiating malignant and benign thyroid nodules:A systematic review and Meta-Analysis[J]. Journal of Biosciences and Medicines, 2021, 9(4):54-76.
    [18]
    Mohorea Iuliana Sobaru, Socea Bogdan, Serban Dragos, et al. Incidence of thyroid carcinomas in an extended retrospective study of 526 autopsies[J]. Experimental and Therapeutic Medicine, 2021, 21(6):607. DOI: 10.3892/etm.2021.10039.
    [19]
    SUTHERLAND R, TSANG V, CLIFTON BLIGH R J, et al. Papillary thyroid microcarcinoma:Is active surveillance always enough?[J]. Clinical Endocrinology, 2021. DOI: 10.1111/cen.14529.
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