ISSN 1004-4140
CN 11-3017/P
| Citation: |
CHEN Yunhui, YANG Yaying, PENG Chao, HU Juan. Advances in CT and MRI Monitoring of Crohn's Disease[J]. CT Theory and Applications, 2021, 30(6): 785-791. DOI: 10.15953/j.ctta.2021-001
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Crohn's disease, with alternating phases of activity and remission holds the characteristics of a long course, complex evolution and extensive involvement,, which have a huge impact on the life quality of patients. How to accurately and comprehensively identify and assess the onset, progression and regression of the disease, such as whether it is in the active phase, the nature of intestinal strictures, and the presence of other systemic lesions, is particularly important to guide treatment. Evaluation modalities that rely solely on clinical indicators or endoscopy are increasingly recognized as flawed by studies. With increased disease awareness and rapid development of examination modalities, the role of medical imaging in this disease cannot be ignored. In this paper we will focus on the value of CT and MRI for monitoring Crohn's disease in active, fibrosis, intestinal luminal strictures, abscess/fistulas, and extragastrointestinal lesions, and also introduce the application of related advanced technologies.
| [1] |
吴慧, 程静云, 王艳, 等. CT肠道成像定量评分系统在回结肠克罗恩病活动性评估中的应用价值[J]. 放射学实践, 2020, 35(1):61-67.
WU H, CHENG J Y, WANG Y, et al. Application value of CT intestinal imaging quantitative scoring system in evaluating the activity of ileocolonic Crohn's disease[J]. Radiology Practice, 2020, 35(1):61-67. (in Chinese).
|
| [2] |
NEHRA A K, SHEEDY S P, WELLS M L, et al. Imaging findings of ileal inflammation at computed tomography and magnetic resonance enterography:What do they mean when ileoscopyand biopsy are negative?[J]. Journal of Crohn's and Colitis, 2020, 14(4):455-464.
|
| [3] |
RIMOLA J, ALVAREZ-COFIÑO A, PÉREZ-JELDRES T, et al. Comparison of three magnetic resonance enterography indices for grading activity in Crohn's disease[J]. Journal of Gastroenterology, 2017, 52(5):585-593.
|
| [4] |
WILLIET N, JARDIN S, ROBLIN X. The simplified magnetic resonance index of activity (MARIA) for Crohn's disease is strongly correlated with the MARIA and clermont score:An external validation[J]. Gastroenterology, 2020, 158(1):282-283.
|
| [5] |
NUNZIA C, ORDÁS I, FERNANDEZ-CLOTET A, et al. Validation of the simplified magnetic resonance index of activity (sMARIA) without gadolinium-enhanced sequences for Crohn's disease[J]. Journal of Crohn's and Colitis, 2020, 14(8):1074-1081.
|
| [6] |
SCHAEFER M, LAURENT V, GRANDMOUGIN A, et al. A magnetic resonance imaging index to predict Crohn's disease postoperative recurrence:The monitor index[J]. Clinical Gastroenterology and Hepatology, 2021, 35(7):132-135.
|
| [7] |
BROUQUET A, RANGHEARD AS, IFERGAN J, et al. The accuracy of preoperative imaging in measuring the length of the ileocolic segment affected by Crohn's disease:A prospective cohort study[J]. Colorectal Disease, 2017, 19(5):437-445.
|
| [8] |
STRAKSYTE V, KIUDELIS G, GINEIKIENE I, et al. Lemann index for assessment of Crohn's disease:Correlation with the quality of life, endoscopic disease activity, magneticresonance index of activity and C-reactive protein[J]. Open Medicine, 2019, 14:785-791.
|
| [9] |
张彩红, 向丽园, 朱建国, 等. 磁共振成像活动性分级与体素内不相干运动在克罗恩病临床评估中的应用[J]. 临床放射学杂志, 2021, 40(8):1539-1544.
ZHANG C H, XIANG L Y, ZHU J G, et al. Application of magnetic resonance imaging activity grading and voxel incoherent motion in clinical evaluation of Crohn's disease[J]. Journal of Clinical Radiology, 2021, 40(8):1539-1544. (in Chinese).
|
| [10] |
HECTORS S J, GORDIC S, SEMAAN S, et al. Diffusion and perfusion MRI quantification in ileal Crohn's disease[J]. European Radiology, 2019, 29(2):993-1002.
|
| [11] |
SCOTT R A, WILLIAMS H G, HOAD C L, et al. MR measures of small bowel wall T2 are associated with increased permeability[J]. Journal of Magnetic Resonance Imaging, 2021, 53(5):1422-1431.
|
| [12] |
LEE S M, KIM S H, AHN S J, et al. Virtual monoenergetic dual-layer, dual-energy CT enterography:Optimization of keV settings and its added value for Crohn's disease[J]. European Radiology, 2018, 28(6):2525-2534.
|
| [13] |
GULER E, UNAL N G, HEKIMSOY I, et al. Dual-energy CT enterography in evaluation of Crohn's disease:The role of virtual monochromatic images[J]. Japanese Journal of Radiology, 2021, 39(4):341-348.
|
| [14] |
DANE B, DUENAS S, HAN J, et al. Crohn's disease activity quantified by iodine density obtained from dual-energy computed tomography enterography[J]. Journal of Computer Assisted Tomography, 2020, 44(2):242-247.
|
| [15] |
DANE B, GARADA A, O'DONNELL T, et al. Crohn disease prognostication with semiautomatic dual-energy computed tomography enterography-derived iodine density[J]. Journal of Computer Assisted Tomography, 2021, 45(2):171-176.
|
| [16] |
Dane B, O'Donnell T, Ream J, et al. Novel dual-energy computed tomography enterography iodine density maps provide unique depiction of Crohn disease activity[J]. Journal of Computer Assisted Tomography, 2020, 44(5):772-779. DOI: 10.1097/RCT.0000000000001009.
|
| [17] |
LI X H, MAO R, HUANG S Y, et al. Ability of DWI to characterize bowel fibrosis depends on the degree of bowel inflammation[J]. European Radiology, 2019, 29(5):2465-2473.
|
| [18] |
DU J F, LU B L, HUANG S Y, et al. A novel identification system combining diffusion kurtosis imaging with conventional magnetic resonance imaging to assess intestinal strictures in patients with Crohn's disease[J]. Abdominal Radiology (NY), 2021, 46(3):936-947.
|
| [19] |
杜金芳, 黄丽, 毛弈涛, 等. 基于MRI扩散峰度成像的列线图预测克罗恩病肠壁纤维化的研究[J]. 中华放射学杂志, 2020, 54(8):792-798.
DU J F, HUANG L, MAO Y, et al. Prediction of intestinal fibrosis in Crohn's disease based on nomogram of MRI diffusion kurtosis imaging[J]. Chinese Journal of Radiology, 2020, 54(8):792-798. (in Chinese).
|
| [20] |
FANG Z N, LI X H, LIN J J, et al. Magnetisation transfer imaging adds information to conventional MRIs to differentiate inflammatory from fibrotic components of small intestinal strictures in Crohn's disease[J]. European Radiology, 2020, 30(4):1938-1947. DOI: 10.1007/bs00330-019-06594-x.
|
| [21] |
MENG J, HUANG S, SUN C, et al. Comparison of three magnetization transfer ratio parameters for assessment of intestinal fibrosis in patients with Crohn's disease[J]. Korean Radiology, 2020, 21(3):290-297.
|
| [22] |
Mazza S, Conforti F S, Forzenigo L V, et al. Agreement between real-time elastography and delayed enhancement magnetic resonance enterography on quantifying bowel wall fibrosis in Crohn's disease[J]. Digestive and Liver Disease, 2021, 43(10):74-77. DOI:10.1016/j.dld.2021. 05.018.
|
| [23] |
LAMBROU T, CHAUDHRY N A, GRAJO J R, et al. Small bowel stricture is associated with abnormal motility on the cine MRI sequence in patients with Crohn's disease[J]. European Radiology, 2019, 118(7):264-270.
|
| [24] |
STOCKER D, KING M J, EL HOMSI M, et al. Luminal narrowing alone allows an accurate diagnosis of Crohn's disease small bowel strictures at cross-sectional imaging[J]. Journal of Crohn's and colitis, 2021, 15(6):1009-1018.
|
| [25] |
SCHULBERG J D, WRIGHT E K, HOLT B A, et al. Magnetic resonance enterography for predicting the clinical course of Crohn's disease strictures[J]. Journal of Gastroenterology and Hepatology, 2020, 35(6):980-987.
|
| [26] |
侍丽, 黄丽, 卢宝兰, 等. 肠系膜爬行脂肪指数与克罗恩炎症性肠道狭窄的相关性分析[J]. 中华放射学杂志, 2021, 55(8):847-852.
SHI L, HUANG L, LU B L, et al. Correlation analysis between mesenteric crawling fat index and Crohn's inflammatory intestinal stenosis[J]. Chinese Journal of Radiology, 2021, 55(8):847-852. (in Chinese).
|
| [27] |
FENG Q, XU X T, ZHOU Y, et al. Creeping fat in patients with ileo-colonic Crohn's disease correlates with disease activity and severity of inflammation:A preliminary study using energy spectral computed tomography[J]. Journal of Digestive Disease, 2018, 19(8):475-484.
|
| [28] |
COSNES J, CATTAN S, BLAIN A, et al. Long-term evolution of disease behavior of Crohn's disease[J]. Inflammatory Bowel Diseases, 2002, 8(4):244-250.
|
| [29] |
PERL D, WALJEE A K, BISHU S, et al. Imaging features associated with failure of nonoperative management of intraabdominal abscesses in Crohn disease[J]. Inflammatory Bowel Diseases, 2019, 25(12):1939-1944. PARK S K, WONG Z, PARK S H, et al. Extraintestinal manifestation of inflammatory bowel disease in Asian patients:A multinational study[J]. Digestive and Liver Disease, 2021, 53(2):196-201.
|
| [30] |
ADAM H, ALQASSAS M, SAADAH O I, et al. Extraintestinal manifestations of inflammatory bowel disease in middle eastern patients[J]. Journal of Epidemiology and Global Health, 2020, 10(4):298-303.
|
| [31] |
KELLY O B, LI N, SMITH M, et al. The prevalence and clinical associations of subclinical sacroiliitis in inflammatory bowel disease[J]. Inflammatory Bowel Diseases, 2019, 25(6):1066-1071.
|
| [32] |
MASSART A, HUNT D P. Pulmonary manifestations of inflammatory bowel disease[J]. The American Journal of Medicine, 2020, 133(1):39-43.
|
| [33] |
AINOUCHE A, DUROT C, SOYER P, et al. Unusual intestinal and extra intestinal findings in Crohn's disease seen on abdominal computed tomography and magnetic resonance enterography[J]. Clinical Imaging, 2020, 59(1):30-38.
|
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