ISSN 1004-4140
CN 11-3017/P
Volume 31 Issue 3
Jun.  2022
Turn off MathJax
Article Contents
ZHANG H, HAN X, CUI B, et al. Predictive value of dual-energy CT left ventricular iodinogram combined with plasma BNP in the development of heart failure after AMI[J]. CT Theory and Applications, 2022, 31(3): 373-382. DOI: 10.15953/j.ctta.2021.068. (in Chinese)
Citation: ZHANG H, HAN X, CUI B, et al. Predictive value of dual-energy CT left ventricular iodinogram combined with plasma BNP in the development of heart failure after AMI[J]. CT Theory and Applications, 2022, 31(3): 373-382. DOI: 10.15953/j.ctta.2021.068. (in Chinese)

Predictive Value of Dual-energy CT Left Ventricular Iodinogram Combined with Plasma BNP in the Development of Heart Failure after AMI

doi: 10.15953/j.ctta.2021.068
  • Received Date: 2021-12-20
  • Accepted Date: 2022-02-16
  • Available Online: 2022-03-05
  • Publish Date: 2022-05-23
  • Objective: To investigate the value of dual-energy CT left ventricular iodinogram imaging and plasma B-type natriuretic peptide level in the early diagnosis and prediction of heart failure and severity in patients with acute myocardial infarction. Methods: AMI patients admitted to our hospital from January 2018 to December 2019 were selected to complete dual-energy coronary artery CTA and plasma BNP examination, and cardiac function grading was assessed within 1 week after admission. Myocardial iodine content was measured to evaluate the myocardial perfusion on dual-energy CT. The correlation between myocardial iodine content, left ventricular ejection fraction and BNP level was analyzed, and the differences of myocardial perfusion, LVEF and BNP levels among different Killip cardiac function grading groups in HF patients were compared. Results: A total of 115 patients with AMI were enrolled, including 42 patients in HF group and 73 patients in non-HF group. There were significant differences in myocardial iodine concentration, LVEF and BNP between the two groups. Iodine concentration and LVEF were negatively correlated with BNP (r=−0.527, −0.674). The ROC curve showed that the AUC of myocardial iodine concentration combined with BNP in predicting HF after AMI was higher than that of iodine map and BNP alone. Among the 42 HF patients after AMI, with the increase of Killip grade, serum BNP level increased, LVEF and iodine content of infarct myocardial decreased, and there were statistically significant differences in BNP, LVEF and iodine content of infarct myocardial among different grade groups. Conclusion: Dual-energy CT left ventricular iodinogram combined with BNP level has predictive value on the occurrence of heart failure after acute myocardial infarction, and has a certain correlation with the clinical severity of heart failure.

     

  • loading
  • [1]
    FACH A, BÜNGER S, ZABROCKI R, et al. Comparison of outcomes of patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention analyzed by age groups (<75, 75 to 85, and >85 years); (Results from the Bremen STEMI Registry)[J]. American Journal of Cardiology, 2015, 116(12): 1802−1809. doi: 10.1016/j.amjcard.2015.09.022
    [2]
    WEIR R, MCMURRAY J J V, VELAZQUEZ E J. Epidemiology of heart failure and left ventricular systolic dysfunction after acute myocardial infarction: Prevalence, clinical characteristics, and prognostic importance[J]. American Journal of Cardiology, 2006, 97(10A): 13F−25F.
    [3]
    DELGADO C, M VÁZQUEZ, OCA R, et al. Myocardial ischemia evaluation with dual-source computed tomography: Comparison with magnetic resonance imaging[J]. Revista Espaola de Cardiología, 2013, 66(11): 864−870.
    [4]
    董宁超, 程国杰, 张弓, 等. 血BNP浓度对急性心肌梗死患者心力衰竭的早期预测效果[J]. 解放军预防医学杂志, 2019,37(6): 163−164.

    DONG N C, CHENG G J, ZHANG G, et al. Effect of serum BNP concentration on early prediction of heart failure in patients with acute myocardial infarction[J]. Journal of Preventive Medicine of Chinese People's Liberation Army, 2019, 37(6): 163−164. (in Chinese).
    [5]
    ISLAM M N, ALAM M F, DEBNATH R C, et al. Correlation between Troponin-I and B-type natriuretic peptide level in acute myocardial infarction patients with heart failure[J]. Mymensingh Medical Journal, 2016, 25(2): 226−231.
    [6]
    RYBICKI F J, UDELSON J E, PEACOCK W F, et al. 2015 ACR/ACC/AHA/AATS/ACEP/ASNC/NASCI/SAEM/SCCT/SCMR/SCPC/SNMMI/STR/STS appropriate utilization of cardiovascular imaging in emergency department patients with chest pain: A joint document of the american college of radiology appropriateness criteria committee and the american college of cardiology appropriate use criteria task force[J]. Journal of the American College of Cardiology, 2016, 67(7): 853−879. doi: 10.1016/j.jacc.2015.09.011
    [7]
    ROFFI M, PATRONO C, COLLET J P, et al. 2015 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)[J]. European Heart Journal, 2016, 37(3): 267−315. doi: 10.1093/eurheartj/ehv320
    [8]
    KIM M S, LEE J H, KIM E J, et al. Korean guidelines for diagnosis and management of chronic heart failure[J]. Korean Circulation Journal, 2017, 47(5): 555−643. doi: 10.4070/kcj.2017.0009
    [9]
    中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 中国心力衰竭诊断和治疗指南2014[J]. 中华心血管病杂志, 2014,42(2): 98−122. doi: 10.3760/cma.j.issn.0253-3758.2014.02.004

    Chinese Society of Cardiology, Editorial Board of Chinese Journal of Cardiology. Chinese guidelines for diagnosis and treatment of heart failure 2014[J]. Chinese Journal of Cardiology, 2014, 42(2): 98−122. (in Chinese). doi: 10.3760/cma.j.issn.0253-3758.2014.02.004
    [10]
    毛懿, 杨跃进, 张健, 等. 急性心肌梗死患者血B型利钠肽水平与心功能的相关性和诊断心力衰竭的价值[J]. 中华心血管病杂志, 2009,37(3): 218−222. doi: 10.3760/cma.j.issn.0253-3758.2009.03.005

    MAO Y, YANG Y J, JIAN Z, et al. The relationship between plasma BNP level and the left ventricular dysfunction parameters in patients with acute myocardial infarction and its value in diagonosing heart failure[J]. Chinese Journal of Cardiology, 2009, 37(3): 218−222. (in Chinese). doi: 10.3760/cma.j.issn.0253-3758.2009.03.005
    [11]
    李睿, 栾波, 段娜, 等. 辽西不同地区急性心肌梗死相关危险因素比较分析[J]. 中国循证心血管医学杂志, 2018,10(3): 300−303. doi: 10.3969/j.issn.1674-4055.2018.03.11

    LI R, LUAN B, DUAN N, et al. Comparative analysis of risk factors related to acute myocardial infarction in different areas of western Liaoning[J]. Chinese Journal of Evidence-Based Cardiovascular Medicine, 2018, 10(3): 300−303. (in Chinese). doi: 10.3969/j.issn.1674-4055.2018.03.11
    [12]
    张胜豪, 刘恒亮, 毛磊, 等. 血清糖类抗原125及脑钠肽水平对心肌梗死后心力衰竭发生及严重程度的预测价值[J]. 中国动脉硬化杂志, 2019,27(1): 55−60. doi: 10.3969/j.issn.1007-3949.2019.01.011

    ZHANG S H, LIU H L, MAO L, et al. Predictive value of serum carbohydrate antigen 125 and brain natriuretic peptide levels in the occurrence and severity of heart failure after myocardial infarction[J]. Chinese Journal of Arteriosclerosis, 2019, 27(1): 55−60. (in Chinese). doi: 10.3969/j.issn.1007-3949.2019.01.011
    [13]
    朱志远, 戴军, 王海燕, 等. 急性心肌梗死患者血清hs CRP/PAB、NT-pro BNP、LVEF水平与心力衰竭发生的相关性[J]. 中国医药导刊, 2019,21(7): 392−395. doi: 10.3969/j.issn.1009-0959.2019.07.003

    ZHU Z Y, DAI J, WANG H Y, et al. Correlation between serum hs CRP/PAB, NT-pro BNP, LVEF Levels and heart failure in patients with acute myocardial infarction[J]. Chinese Journal of Medicinal Guide, 2019, 21(7): 392−395. (in Chinese). doi: 10.3969/j.issn.1009-0959.2019.07.003
    [14]
    DANAD I, SZYMONIFKA J, SCHULMAN-MARCUS J, et al. Static and dynamic assessment of myocardial perfusion by computed tomography[J]. European Heart Journal Cardiovasc Imaging, 2016, 17(8): 836−844. doi: 10.1093/ehjci/jew044
    [15]
    韩瑞娟, 孙凯, 李坤成, 等. 第二代双源CT双能量心肌灌注成像对心肌梗死的诊断价值[J]. 中华诊断学电子杂志, 2015,3(3): 17−21.

    HAN R J, SUN K, LI K C, et al. Diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction[J]. Chinese Journal of Diagnostics (Electronic Edition), 2015, 3(3): 17−21. (in Chinese).
    [16]
    SCHWARZ F, RUZSICS B, SCHOEPF U J, et al. Dual-energy CT of the heart−Principles and protocols[J]. European Journal of Radiology, 2008, 68(3): 423−433. doi: 10.1016/j.ejrad.2008.09.010
    [17]
    HO K T, ONG H Y, TAN G, et al. Dynamic CT myocardial perfusion measurements of resting and hyperaemic blood flow in low-risk subjects with 128-slice dual-source CT[J]. European Heart Journal Cardiovasc Imaging, 2015, 16(3): 300−306. doi: 10.1093/ehjci/jeu200
    [18]
    NICCOLI G, SCALONE G, LERMAN A, et al. Coronary microvascular obstruction in acute myocardial infarction[J]. European Heart Journal, 2016, 37(13): 1024−1033. doi: 10.1093/eurheartj/ehv484
    [19]
    马海彦, 王玉权, 谢光友, 等. 动态CT心肌灌注成像定量心肌血流量与ST段抬高心肌梗死患者肌钙蛋白水平及左心室功能受损的相关性[J]. 实用医学杂志, 2020,36(10): 1371−1375. doi: 10.3969/j.issn.1006-5725.2020.10.020

    MA H Y, WANG Y Q, XIE G Y, et al. Dynamic CT myocardial perfusion imaging with quantitative MBF correlated with troponin level and impaired left ventricular function in patients with ST− Segment elevation myocardial infarction[J]. Journal of Practical Medicine, 2020, 36(10): 1371−1375. (in Chinese). doi: 10.3969/j.issn.1006-5725.2020.10.020
    [20]
    MEINEL F G, PUGLIESE F, SCHOEPF U J, et al. Prognostic value of stress dynamic myocardial perfusion CT in a multicenter population with known or suspected coronary artery disease[J]. American Journal of Cardiology, 2017, 208(4): 761−769.
    [21]
    赵娜, 高扬. 心脏功能学CT成像技术的研究及应用现状[J]. 中国循环杂志, 2020,35(11): 1139−1143. doi: 10.3969/j.issn.1000-3614.2020.11.016

    ZHAO N, GAO Y. Research and application status of CT imaging in cardiac function[J]. Chinese Circulation Journal, 2020, 35(11): 1139−1143. (in Chinese). doi: 10.3969/j.issn.1000-3614.2020.11.016
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(3)  / Tables(5)

    Article Metrics

    Article Views(110) PDF Downloads(8) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return