ISSN 1004-4140
CN 11-3017/P
Volume 31 Issue 5
Sep.  2022
Turn off MathJax
Article Contents
Abstract
References
Related Articles
ZHANG J, ZHANG T, LI H L, et al. The characteristics and its potential application value of pancreatic ductal adenocarcinoma with single-source dual energy spectral CT imaging[J]. CT Theory and Applications, 2022, 31(5): 647-654. DOI: 10.15953/j.ctta.2022.049. (in Chinese).
Citation: ZHANG J, ZHANG T, LI H L, et al. The characteristics and its potential application value of pancreatic ductal adenocarcinoma with single-source dual energy spectral CT imaging[J]. CT Theory and Applications, 2022, 31(5): 647-654. DOI: 10.15953/j.ctta.2022.049. (in Chinese).
shu

The Characteristics and Its Potential Application Value of Pancreatic Ductal Adenocarcinoma with Single-source Dual Energy Spectral CT Imaging

  • 1.

    Affiliated RuiJin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025, China Department of Radiology

  • 2.

    Affiliated RuiJin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025, China Department of Pathology

  • 3.

    Affiliated RuiJin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025, China Department of Nuclear Medicine

  • 2.

    Shanghai Baoshan Medical Emergency Center, Shanghai 201901, China

More Information
  • Received Date: March 19, 2022
  • Revised Date: May 21, 2022
  • Accepted Date: May 22, 2022
  • Available Online: June 21, 2022
  • Published Date: September 30, 2022
    Graphical Abstract
    • Abstract
  • Objective: To study the quantitative multi-parameters of CT energy spectrum imaging of pancreatic ductal adenocarcinoma by using enhanced CT energy spectrum imaging, and to explore the parameter characteristics and potential application value of CT energy spectrum imaging of pancreatic ductal adenocarcinoma. Methods: Retrospective analysis was performed on 61 patients with pancreatic ductal adenocarcinoma confirmed by pathology, all of whom underwent enhanced CT scan of advanced arterial and portal vein phase. Single energy CT value, Effective atomic number (Effective-Z), iodine (water) base value and water (iodine) base value of pancreatic cancer lesions and pancreatic parenchyma were recorded. Paired t test (normal distribution) or Wilcoxon signed-rank sum test (non-normal distribution) were used to compare the differences of the above CT energy spectrum imaging parameters between the late arterial period and portal vein period, pancreatic cancer and pancreatic parenchyma, and to plot the corresponding energy spectrum curves. Results: The single energy CT value of pancreatic ductal adenocarcinoma in advanced arterial stage was significantly lower than that in peripheral normal pancreas. The single energy CT value of pancreatic ductal adenocarcinoma in portal vein stage was higher than that in arterial stage and lower than that in peripheral normal pancreas. The lower the low energy segment is, the more significant the difference is. The higher the energy segment is, the smaller the difference is. There were significant differences in single energy CT value, paired base substance iodine (water) base value and Effective-Z corresponding homogenization concentration between pancreatic ductal adenocarcinoma and pancreatic parenchyma in arteriovenous phase, while there was no significant difference in water (iodine) value. Conclusion: The dual-phase enhanced energy spectrum parameters of CT imaging of pancreatic ductal adenocarcinoma have certain characteristics. The single energy CT value, iodine (water) base value and effective atomic number of pancreatic cancer in arteriovenous phase were lower than those in corresponding pancreatic parenchyma, and those in arterial late phase were lower than those in portal vein phase. The lower the energy segment, the more obvious the difference. The comprehensive application of multi-band and energy spectrum multi parameter imaging is helpful to improve the CT density resolution of pancreatic ductal adenocarcinoma, and has the potential value of providing image information for early diagnosis of small pancreatic cancer.
    • FullText(HTML)
    • References (13)
  • [1]
    LI W X, MIAO F, XU X Q, et al. Pancreatic euroendocrine Neoplasms: CT spectral imaging in grading[J]. Academic Radiology, 2021, 28(2): 208−216. DOI: 10.1016/j.acra.2020.01.033.Epub2020Feb26.
    [2]
    高回青, 胡春洪, 郁义星, 等. 能谱CT定量分析在鉴别肝癌和肝脓肿中的价值[J]. 中华肝脏病杂志, 2016,24(9): 676−680. DOI: 10.3760/cma.j.issn.1007-3418.2016.09.008.

    GAO H Q, HU C H, YU Y X, et al. Value of spectral CT-based quantitative analysis in differential diagnosis of liver cancer and liver abscess[J]. Chinese Journal of Hepatology, 2016, 24(9): 676−680. DOI: 10.3760/cma.j.issn.1007-3418.2016.09.008. (in Chinese).
    [3]
    尹伟, 张倩雯, 许兵, 等. 宽探测器多层螺旋CT靶扫描技术在胰腺癌术前评估中的应用价值[J]. 中华胰腺病杂志, 2021,21(4): 276−281. DOI: 10.3760/cma.j.cn115667-20210304-00046.

    YIN W, ZHANG Q W, XU B, et al. Application value of wide detector CT target scanning technique in the preoperative evaluation of pancreatic cancer[J]. Chinese Journal of Pancreatology, 2021, 21(4): 276−281. DOI: 10.3760/cma.j.cn115667-20210304-00046. (in Chinese).
    [4]
    李楠, 吕瑛. 内镜超声在小胰腺癌中的诊断价值[J]. 中华胰腺病杂志, 2020,20(1): 8−11. DOI: 10.3760/cma.j.issn.1674-1935.2020.01.002.

    LI N, LV Y. Diagnostic value of endoscopic ultrasound for small pancreatic cancer[J]. Chinese Journal of Pancreatology, 2020, 20(1): 8−11. DOI: 10.3760/cma.j.issn.1674-1935.2020.01.002. (in Chinese).
    [5]
    谢环环, 林晓珠, 王晴柔, 等. 胰腺导管上皮腺癌的CT能谱成像定量参数特征[J]. 中华放射学杂志, 2017,51(3): 170−173. DOI: 10.3760/cma.j.issn.1005-1201.2017.03.003.

    XIE H H, LIN X Z, WANG Q R, et al. The characteristics of pancreatic ductal adenocarcinoma with single-source dual energy spectral CT imaging[J]. Chinese Journal of Radiology, 2017, 51(3): 170−173. DOI: 10.3760/cma.j.issn.1005-1201.2017.03.003. (in Chinese).
    [6]
    张静, 李宏磊, 张婷, 等. 能谱CT多参数成像在胰岛素瘤定位中的比较研究[J]. CT理论与应用研究, 2019,28(4): 471−476. DOI: 10.15953/j.1004-4140.2019.28.04.08.

    ZHANG J, LI H L, ZHANG T, et al. Comparison in localization of pancreatic insulinoma by the multiparameter of dual energy spectral CT imaging[J]. CT Theory and Applications, 2019, 28(4): 471−476. DOI: 10.15953/j.1004-4140.2019.28.04.08. (in Chinese).
    [7]
    张静, 林晓珠, 陈克敏, 等. MRI和能谱CT成像在胰岛素瘤诊断中的初步研究[J]. 临床放射学杂志, 2014,33(3): 368−372. DOI: 10.13437/j.cnki.jcr.2014.03.015.

    ZHANG J, LIN X Z, CHEN K M, et al. Comparative study of MRI imaging and spectral CT imaging in the diagnosis of insulinoma[J]. Journal of Clinical Radiology, 2014, 33(3): 368−372. DOI: 10.13437/j.cnki.jcr.2014.03.015. (in Chinese).
    [8]
    董海鹏, 林晓珠, 徐学勤, 等. 腺假性囊肿的CT能谱特征[J]. 中国医学计算机成像杂志, 2013,19(1): 53−56. DOI: 10.3969/j.issn.1006-5741.2013.01.013.

    DONG H P, LIN X Z, XU X Q, et al. Spectral CT imaging of pancreatic pseudo-cyst[J]. Chinese Computed Medical Imaging, 2013, 19(1): 53−56. DOI: 10.3969/j.issn.1006-5741.2013.01.013. (in Chinese).
    [9]
    林晓珠, 陈克敏, 吴志远, 等. CT能谱成像在鉴别胰腺寡囊型浆液性囊腺瘤与黏液性囊性肿瘤中的价值[J]. 中华放射学杂志, 2011,45(8): 713−717. DOI: 10.3760/cma.j.issn.1005-1201.2011.08.002.

    LIN X Z, CHEN K M, WU Z Y, et al. Spectral CT imaging in differential diagnosis of pancreatic serous oligocystic adenoma and mucinous cystic neoplasms[J]. Chinese Journal of Radiology, 2011, 45(8): 713−717. DOI: 10.3760/cma.j.issn.1005-1201.2011.08.002. (in Chinese).
    [10]
    ZHANG L, SANAGAPALLI S, STOITA A. Challenges in diagnosis of pancreatic cancer[J]. World Journal of Gastroenterology, 2018, 24(19): 2047−2060. DOI: 10.3748/wjg.v24.i19.2047.
    [11]
    SRISAJJAKUL S, PRAPAISILP P, BANGCHOKDEE S. CT and MR features that can help to differentiate between focal chronic pancreatitis and pancreatic cancer[J]. La Radiologia Medica, 2020, 125(4): 356−364. DOI: 10.1007/s11547-019-01132-7.Epub2020Jan13.
    [12]
    BALCI N C, SEMELKA R C. Radiologic diagnosis and staging of pancreatic ductal adenocarcinoma[J]. European Journal of Radiology, 2001, 38(2): 105−112. DOI: 10.1016/s0720-048x(01)00295-9.
    [13]
    El KAYAL N, LENNARTZ S, EKDAWI S, et al. Value of spectral detector computed tomography for assessment of pancreatic lesions[J]. European Journal of Radiology, 2019, 118: 215−222. DOI: 10.1016/j.ejrad.2019.07.016.Epub2019Jul16.
    • Related Articles

  • Related Articles

    [1]YAN Qinwen, WANG Yuxiang, ZHANG Jun, HE Lan, HU Gang, XIONG Minchao, QIN Junxiang, YUAN Xuegang. Clinical Value of Spectral Imaging Combined with MAR for CTA after Embolization of Intracranial Aneurysms[J]. CT Theory and Applications, 2024, 33(2): 182-188. DOI: 10.15953/j.ctta.2023.035
    [2]CHEN Xiaoyong, XU Jingci, LI Qinqin, PAN Zilai. The Predictive Value of CT Findings in Invasive Behavior of Pancreatic Neuroendocrine Tumors[J]. CT Theory and Applications, 2022, 31(3): 399-407. DOI: 10.15953/j.ctta.2021.082
    [3]QIU Gan-bin, MA Li-heng, JI Ya-yun, LIANG Yu-ying, LIU Mou-yuan. CT Imaging Findings Neuroendocrine Tumors of Pancreas[J]. CT Theory and Applications, 2018, 27(6): 759-766. DOI: 10.15953/j.1004-4140.2018.27.06.09
    [4]DENG Xiao-lin, XIE Hui, QU Ya-lin, YANG Shao-wei, YANG Zheng-bin. Spectral CT with Optimal Monochromatic Energy to Improve CTA Image Quality of Head and Neck[J]. CT Theory and Applications, 2018, 27(6): 719-726. DOI: 10.15953/j.1004-4140.2018.27.06.05
    [5]ZHANG Liu, LI Shao-dong, WANG Wen-tao, ZHANG Xue. Application of MSCT in the Diagnosis of Solid Pseudopapillary Tumour of Pancreas on Children[J]. CT Theory and Applications, 2018, 27(4): 511-517. DOI: 10.15953/j.1004-4140.2018.27.04.12
    [6]FAN Bing, WANG Xiao-ying, QIU Jian-xing, GUO Xiao-chao, DONG Jian, GONG Kan. Evaluation of Urinary Calculi: A Comparison of CT Values between Spectrum CT and Conventional CT[J]. CT Theory and Applications, 2016, 25(4): 403-408. DOI: 10.15953/j.1004-4140.2016.25.04.03
    [7]WANG Rui, HU Chan-chan, YIN Xiao-ming, CENG Qing-yu. The Application of CT Spectrum Imaging for Diagnosis of Squamous Cell Carcinoma and Adenoid Cystic Carcinoma in Central Airway[J]. CT Theory and Applications, 2015, 24(6): 785-792. DOI: 10.15953/j.1004-4140.2015.24.06.03
    [8]WU De-hong, CHEN Shao-bo, MU Hua-guo, GONG Xiao-hong, FU Chuan-ming, CHEN Wen. CT and MRI Manifestations of Autoimmune Pancreatitis[J]. CT Theory and Applications, 2015, 24(4): 611-619. DOI: 10.15953/j.1004-4140.2015.24.04.16
    [9]LI Jing-ying, WANG Xiu-ling, WU Meng. Imaging Features of Solid Pseudopapillary Tumor of the Pancreas on Computed Tomography and Magnetic Resonance Imaging[J]. CT Theory and Applications, 2013, 22(1): 161-166.
    [10]ZHAN Yong, XIANG Zi-yun, WANG Jing-bo, ZHU Yu-hui, YANG Xue. CT Diagnosis of Intraductal Papillary Mucinous Neoplasm of Pancreas[J]. CT Theory and Applications, 2010, 19(4): 85-90.

Catalog

    Get Citation
    PDF
    XML
    Article views (280) PDF downloads (24) Cited by()
    Related

    Website Copyright © Editorial Office of Computerized Tomography Theory and Applications

    Address：No.5 Minzudaxue Nanlu,Haidian District,Beijing 100081,P.R.China（100081）

    E-mail：cttacn@cea-igp.ac.cn

    Phone：010-68729234

    京ICP备08002722号-11

    震球期刊
    CT理论与应用研究-中英文
    E-mail
    RSS

    Supported by: Beijing Renhe Information Technology Co. Ltd     Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return