EBV Infection Associated Neoplastic Lesions and Imaging Characteristics

YU Tong; WANG Yan; HONG Tianyu; ZHANG Hong; DUAN Xiaomin

doi:10.15953/j.ctta.2022.104

Volume 31 Issue 4

Jul. 2022

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CT Theory and Applications > 2022 > 31(4): 517-530. > DOI: 10.15953/j.ctta.2022.104

YU T, WANG Y, HONG T Y, et al. EBV infection associated neoplastic lesions and imaging characteristics[J]. CT Theory and Applications, 2022, 31(4): 517-530. DOI: 10.15953/j.ctta.2022.104. (in Chinese).

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EBV Infection Associated Neoplastic Lesions and Imaging Characteristics

Department of Radiology, Beijing Children’s Hospital, Capital Medical University/National Center for Children’s Health, Beijing 100045, China

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Received Date: May 29, 2022
Revised Date: June 25, 2022
Accepted Date: July 10, 2022
Available Online: July 19, 2022
Published Date: July 31, 2022

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Abstract

Abstract

Epstein-Barr virus (EBV), also known as a gamma herpesviru, has the characteristics of lymphophilic tissue. EBV is one of the most common human viruses of the human cold virus group and the first human tumor virus found. Infection with EBV occurs by the oral transfer of saliva and respiratory secretions. Human B-lymphocytes and epithelial cells are EBV-susceptible host cells. First EBV infection often occurs in infancy and in childhood. EBV-associated diseases include infectious mononucleosis, EB virus associated hemophagocytic lymphoproliferative disorder (EBV-HLH), chronic active EBV Infection, EBV infection-associated autoimmune disease. EBV infection can also cause the proliferative diseases of the infected cells, such as various non-malignant lymphoproliferative diseases, lymphomatoid granulomatosis, EBV associated with many more malignant diseases including Burkitt′s lymphoma, Hodgkin′s lymphoma, Diffuse Large B-Cell Lymphoma, NK/T cell lymphoma, nasopharyngeal carcinoma, a subset of gastric carcinomas, and many more. This paper mainly focuses on EBV associated lymphoproliferative diseases and imaging characteristics in children.
- radiology,
- child,
- Epstein-Barr virus,
- Epstein-Barr virus associated lymphoproliferative diseases

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