ISSN 1004-4140
CN 11-3017/P
Volume 31 Issue 4
Jul.  2022
Turn off MathJax
Article Contents
Abstract
References
Related Articles
DONG J, XIN J F, YUAN G X, et al. CT lymphangiography (CTL) in different type of primary intestinal lymphangiectasia (PIL): A comparative study[J]. CT Theory and Applications, 2022, 31(4): 469-477. DOI: 10.15953/j.ctta.2022.115. (in Chinese).
Citation: DONG J, XIN J F, YUAN G X, et al. CT lymphangiography (CTL) in different type of primary intestinal lymphangiectasia (PIL): A comparative study[J]. CT Theory and Applications, 2022, 31(4): 469-477. DOI: 10.15953/j.ctta.2022.115. (in Chinese).
shu

CT Lymphangiography (CTL) in Different Type of Primary Intestinal Lymphangiectasia (PIL): A Comparative Study

  • 1.

    Capital Medical University, Beijing 100038, China Department of Radiology

  • 2.

    Capital Medical University, Beijing 100038, China Department of Lymph Surgery, Beijing Shijitan Hospital

  • 2.

    Department of Radiology, Hanting People’s Hospital, Weifang 261199, China

More Information
  • Received Date: June 11, 2022
  • Revised Date: June 24, 2022
  • Accepted Date: June 29, 2022
  • Available Online: July 05, 2022
  • Published Date: July 31, 2022
    Graphical Abstract
    • Abstract
  • Objective: To explore the clinical and imaging characteristics and application value CT lymphangiography (CTL) in patients with different types of primary intestinal lymphangiectasia (PIL). Methods: Patients diagnosed as PIL in our center were recruited in this retrospective study from January 2016 to December 2019, All CTL data were blindly reviewed by two radiologists separately, and the evaluation indicators included: sex, onset age, symptoms and signs, serum albumin, wall thickening, serous cavity effusion, abnormal distribution of lymphatics, lymph reflux, lymph nodes, fistula and abnormal lymphatics around neck area. Based on the abnormal lymphatics in intestinal wall and/or mesentery, PIL was classified into type Ⅰ (positive type) and type Ⅱ (negative type). The clinical and imaging features were compared between the two groups. Results: 34 PIL patients were recruited in this study, including 15 cases of Ⅰ and 19 cases of Ⅱ. Type I showed older age of first onset (15.3±9.4 vs. 8.3±3.8), higher rate of diarrhea, and lower rate of limb and/or facial edema than type Ⅱ, with no statistical difference in sex and serum albumin. For imaging features comparisons, type Ⅰ demonstrated higher rate of abnormal dilated lymphatics and fistula, lower rate of increased attenuation of mesentery and lymph nodes, while no statistical difference was found between wall thickening, serous cavity effusion, lymph reflux and abnormal dilated lymphatics around neck area. Conclusion: CTL demonstrated capability of evaluation in detection of location, distribution and range of abnormal lymphatics in PIL. Based on CTL, the imaging classification of PIL was proposed. Different types of PIL showed different clinical and imaging features, which was useful for therapeutic adoptions.
    • FullText(HTML)
    • References (21)
  • [1]
    GONZALEZ N R, DOMINGUEZ C A, ALCOBA V L, et al. Primary intestinal lymphangiectasia: A rare disease as a cause of protein-losing enteropathy[J]. Revista Espanola de Enfermedades Digestivas, 2022. DOI:10.17235/reed.2022.8673/2022. (Online ahead of print).
    [2]
    KHAYAT A A. Primary intestinal lymphangiectasia presenting as limb hemihyperplasia: A case report and literature review[J]. BMC Gastroenterol, 2021, 21(1): 225. doi: 10.1186/s12876-021-01813-6
    [3]
    BORZUTZKY A, ESPINO A, ALBERTI G, et al. Primary intestinal lymphangiectasia (Waldmann's Disease)[J]. American Journal of Gastroenterology, 2019, 114(2): 197. doi: 10.1038/s41395-018-0413-0
    [4]
    YANG C, DEHNER L P. Protein-losing enteropathy with intestinal lymphangiectasia in skeletal dysplasia with Lys650 Met mutation[J]. American Journal of Medical Genetics Part A, 2016, 170(11): 2993−2997. doi: 10.1002/ajmg.a.37756
    [5]
    CRUTZEN B, PONCELET P A. Protein-losing enteropathy in primary lymphangiectasia[J]. Journal of the Belgian Society of Radiology, 2020, 104(1): 34. doi: 10.5334/jbsr.2136
    [6]
    LOPEZ R N, DAY A S. Primary intestinal lymphangiectasia in children: A review[J]. Journal of Paediatrics and Child Health, 2020, 56(11): 1719−1723. doi: 10.1111/jpc.14837
    [7]
    MANORIA P, GULWANI H V. Primary intestinal lymphangiectasia in a middle-aged female[J]. Saudi Jorunal Medicine & Medical Sciences, 2021, 9(3): 280−281.
    [8]
    HUBER R, SEMMLER G, MAYR A, et al. Primary intestinal lymphangiectasia in an adult patient: A case report and review of literature[J]. World Journal of Gastroenterology, 2020, 26(48): 7707−7718. doi: 10.3748/wjg.v26.i48.7707
    [9]
    PRASAD D, SRIVASTAVA A, TAMBE A, et al. Clinical profile, response to therapy, and outcome of children with primary intestinal lymphangiectasia[J]. Digestive Diseases, 2019, 37(6): 458−466. doi: 10.1159/000499450
    [10]
    CRAVEN M D, WASHABAU R J. Comparative pathophysiology and management of protein-losing enteropathy[J]. Journal of Veterinary Internal Medicine, 2019, 33(2): 383−402. doi: 10.1111/jvim.15406
    [11]
    KAKIUCHI T, MIZUOCHI T, KOJI A, et al. Long-term endoscopic findings in pediatric primary intestinal lymphangiectasia[J]. Clinical Case Reports, 2021, 9(2): 1029−1030. doi: 10.1002/ccr3.3619
    [12]
    CUNNINGHAM J M, NEPAL S, TRUESDALE A E. Primary intestinal lymphangiectasia diagnosed by video capsule endoscopy in a patient with immunodeficiency presenting with morganella morganii bacteraemia[J]. BMJ Case Reports, 2020, 13(9): e235898. doi: 10.1136/bcr-2020-235898
    [13]
    TOMINAGA K, TSUCHIYA A, KAWATA Y, et al. Novel magnified single-balloon enteroscopy enables observation of jejunal white spots associated with lymphangiectasia[J]. Digestive Diseases, 2019, 37(2): 170−174. doi: 10.1159/000493578
    [14]
    Van der REIJDEN S M, van WIJK M P, JACOBS M, et al. Video capsule endoscopy to diagnose primary intestinal lymphangiectasia in a 14-month-old child[J]. Journal of Pediatric Gastroenterology and Nutrition, 2017, 64(6): e161. doi: 10.1097/MPG.0000000000001586
    [15]
    BROWNELL J N, BIKO D M, MAMULA P, et al. Dynamic contrast magnetic resonance lymphangiography localizes lymphatic leak to the duodenum in protein-losing enteropathy[J]. Journal of Pediatric Gastroenterology and Nutrition, 2022, 74(1): 38−45. doi: 10.1097/MPG.0000000000003287
    [16]
    DONG J, XIN J, SHEN W, et al. Unipedal diagnostic lymphangiography followed by sequential ct examinations in patients with idiopathic chyluria: A retrospective study[J]. American Journal of Roentgenology, 2018: 210(4): 792-798.
    [17]
    董健, 信建峰, 霍萌, 等. 直接淋巴管造影和CT淋巴管成像在乳糜尿中的诊断价值[J]. 临床放射学杂志, 2018,37(5): 798−802. doi: 10.13437/j.cnki.jcr.2018.05.020

    DONG J, XIN J F, HUO M, et al. Direct lymphangiography with sequential CT lymphangiography in chyluria: A retrospective study[J]. Clinical Radiology, 2018, 37(5): 798−802. (in Chinese). doi: 10.13437/j.cnki.jcr.2018.05.020
    [18]
    董健, 沈文彬, 信建峰, 等. 联合应用CT淋巴管成像与直接淋巴管造影诊断原发性小肠淋巴管扩张症的价值[J]. 中华放射学杂志, 2017,51(5): 362−365. doi: 10.3760/cma.j.issn.1005-1201.2017.05.008

    DONG J, SHEN W B, XIN J F, et al. Value of CT lymphangiography combined with direct lymphangiography in diagnosing primary intestinal lymphangiectasia[J]. Journal of Chinese Radiology, 2017, 51(5): 362−365. (in Chinese). doi: 10.3760/cma.j.issn.1005-1201.2017.05.008
    [19]
    DONG J, XIN J, SHEN W, et al. CT lymphangiography (CTL) in primary intestinal lymphangiectasia (PIL): A comparative study with intraoperative enteroscopy (IOE)[J]. Academic Radiology, 2019, 26(2): 275−281. doi: 10.1016/j.acra.2018.04.023
    [20]
    董健, 信建峰, 张春燕, 等. 直接淋巴管造影术后CT在原发性小肠淋巴管扩张症中的回顾性研究[J]. 临床放射学杂志, 2018,37(9): 1510−1514.

    DONG J, XIN J, ZHANG C Y, et al. Post-lymphangiographic CT (PLCT) in primary intestinal lymphangiectasia: A retrospective study[J]. Clinical Radiology, 2018, 37(9): 1510−1514. (in Chinese).
    [21]
    董健, 信建峰, 霍萌, 等. 直接淋巴管造影与CT淋巴管成像在继发性小肠淋巴管扩张症的回顾性研究[J]. 临床放射学杂志, 2018,37(3): 419−423. doi: 10.13437/j.cnki.jcr.2018.03.014

    DONG J, XIN J, HUO M, et al. Direct lymphangiography with sequential CT lymphangiography in secondary intestinal lymphangiectasia: A retrospective study[J]. Clinical Radiology, 2018, 37(3): 419−423. (in Chinese). doi: 10.13437/j.cnki.jcr.2018.03.014
    • Related Articles

  • Related Articles

    [1]HAO Qi, ZHANG Yan, LI Xingpeng, LIU Mengke, SUN Xiaoli, WANG Rengui. The Application Value of CT Lymphangiography in Diagnosis and Grading in Patients with Primary Chyluria[J]. CT Theory and Applications, 2022, 31(4): 459-468. DOI: 10.15953/j.ctta.2022.106
    [2]ZHANG Yan, HAO Qi, LIU Mengke, LI Xingpeng, SUN Xiaoli, WANG Rengui. Application of CT Lymphangiography in the Diagnosiis of Primary Pulmonary Lymphedema[J]. CT Theory and Applications, 2022, 31(4): 441-447. DOI: 10.15953/j.ctta.2022.096
    [3]GUO Jia, ZHANG Yan, LIU Mengke, LI Xingpeng, HAO Qi, WANG Rengui. CT and CT Lymphangiography Findings of Congenital Pulmonary Lymphangiectasis[J]. CT Theory and Applications, 2022, 31(4): 433-440. DOI: 10.15953/j.ctta.2022.116
    [4]YU Xingyao, LIU Chao, FENG Qianqian, XU Lin. The Value of MSCT Signs in Differential Diagnosis of Pathological Types of Acute Appendicitis[J]. CT Theory and Applications, 2022, 31(2): 251-258. DOI: 10.15953/j.1004-4140.2022.31.02.13
    [5]LI Ya-chao, YU Bei, LI Xiao-li. The Relationship of between Subacromial Impingement Syndrome and Shoulder Typing under MSCT[J]. CT Theory and Applications, 2015, 24(5): 753-759. DOI: 10.15953/j.1004-4140.2015.24.05.14
    [6]WU De-hong, YANG Song, GONG Xiao-hong, FU Chuan-ming, LIU Chao, CHEN Ping-you. The CT Diagnosis of Cystic Type Intestinal Duplications[J]. CT Theory and Applications, 2014, 23(5): 871-876.
    [7]WU Meng-nan, PENG Zhen-peng, HU Xiao-shu, DONG Zhi, LUO Yan-ji, FENG Shi-ting, YANG Xu-feng. The Classification Diagnosis of CT and its Imaging Features in Infantile Hepatic Hemangioendothelioma[J]. CT Theory and Applications, 2014, 23(4): 663-668.
    [8]SHI Ying-qin, PAN Jin-xiao. The Research of Reconstruction Speed for the Feldkamp-type-VOI Algorithm[J]. CT Theory and Applications, 2011, 20(1): 55-61.
    [9]WANG Ge, Seung WookLee. Grangeat-Type and Katsevich-Type Algorithms for Cone-Beam CT[J]. CT Theory and Applications, 2003, 12(2): 45-55.
    [10]Wang Hong-sheng, Wang Feng-yun. A Signification of Sediment Grouping after TACE Intraarterial Infusion of Iodized Oil[J]. CT Theory and Applications, 2001, 10(1): 5-7.

  • Cited by

    Periodical cited type(2)

    1. 武占鑫. 纵隔支气管源性囊肿的CT诊断特点分析. 影像研究与医学应用. 2025(01): 136-138 .
    2. 陈君如，刀娅，杨仕武，王舒钰，代如涛，张熙晨，胡玉磊，马永钰，吴骏. 基于三维重建技术胸腔镜治疗婴儿复杂解剖支气管源性囊肿1例. 中国微创外科杂志. 2024(12): 846-848 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (398) PDF downloads (21) Cited by(2)
    Related

    Website Copyright © Editorial Office of Computerized Tomography Theory and Applications

    Address：No.5 Minzudaxue Nanlu,Haidian District,Beijing 100081,P.R.China（100081）

    E-mail：cttacn@cea-igp.ac.cn

    Phone：010-68729234

    京ICP备08002722号-11

    Supported by: Beijing Renhe Information Technology Co. Ltd     Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return