ISSN 1004-4140
CN 11-3017/P
Volume 32 Issue 2
Mar.  2023
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ZHAO X S, MIAO F, SUN J, et al. The Diagnosis of Cronkhite-Canada Syndrome with CT Enterography: A Clinical Case Analysis[J]. CT Theory and Applications, 2023, 32(2): 263-270. DOI: 10.15953/j.ctta.2023.017. (in Chinese).
Citation: ZHAO X S, MIAO F, SUN J, et al. The Diagnosis of Cronkhite-Canada Syndrome with CT Enterography: A Clinical Case Analysis[J]. CT Theory and Applications, 2023, 32(2): 263-270. DOI: 10.15953/j.ctta.2023.017. (in Chinese).
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The Diagnosis of Cronkhite-Canada Syndrome with CT Enterography: A Clinical Case Analysis

  • 1.

    Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200025, China Department of Radiology

  • 2.

    Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200025, China Department of Gastroenterology

  • 3.

    Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200025, China Department of Pathology

More Information
  • Received Date: February 10, 2023
  • Revised Date: February 12, 2023
  • Accepted Date: February 13, 2023
  • Available Online: February 21, 2023
  • Published Date: March 30, 2023
    Graphical Abstract
    • Abstract
  • Cronkhite-Canada syndrome (CCS) is a rare cause of chronic diarrhea and malabsorption where patients develop multiple polyps throughout the gastrointestinal (GI) tract, accompanied by ectodermal changes. Due to its rarity, its early detection and diagnosis can be challenging for physicians. This case report described a 58-year-old male patient with CCS who presented with chronic watery diarrhea, hematochezia, weight loss, and skin changes including nail dystrophy and hyperpigmen-tation. Laboratory results showed anemia and hypoalbuminemia. He underwent CT enterography (CTE) which identified diffuse edematous polyposis in the GI tract. The CTE results were highly suspicious of CCS and a subsequent endoscopic examination confirmed the diagnosis. The patient received supportive treatment which improved his symptoms. Based on CTE and endoscopy at 1-year follow-up, the patient was deemed to be in remission. We included a literature review of CCS. The case report aimed to improve the understanding of CCS and explored the key CTE features relevant to its early diagnosis.
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    • References (15)
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