ISSN 1004-4140
CN 11-3017/P
WU W Z, FANG T S, LIANG Z H, et al. Quantitative Computed Tomography Study of Bone Mineral Density for Adults Residents in Foshan[J]. CT Theory and Applications, 2024, 33(2): 213-220. DOI: 10.15953/j.ctta.2023.098. (in Chinese).
Citation: WU W Z, FANG T S, LIANG Z H, et al. Quantitative Computed Tomography Study of Bone Mineral Density for Adults Residents in Foshan[J]. CT Theory and Applications, 2024, 33(2): 213-220. DOI: 10.15953/j.ctta.2023.098. (in Chinese).

Quantitative Computed Tomography Study of Bone Mineral Density for Adults Residents in Foshan

More Information
  • Received Date: April 23, 2023
  • Revised Date: July 27, 2023
  • Accepted Date: July 27, 2023
  • Available Online: August 08, 2023
  • Objective: To study the relation between adult vertebral bone mineral density (BMD) and gender and age in Foshan, to explore the average BMD of each age group and osteoporosis (OP) incidence distribution in the region. Methods: Quantitative computed tomography (QCT) was used to examine and record the vertebral BMD of 1065 (male 648, female 417) healthy adults who underwent physical examination in Foshan Hospital of TCM from October 2021 to March 2023, and grouped according to age, T test and variance analysis were used on BMD in different sex and age group. Chi square analysis and correlation analysis were used on the incidence of OP in different sex and age group. Results: There was significant difference in the BMD between male and female of 20~29, 30~39, 40~49 and 60~69, 70~79 years old, women had higher peak BMD than man in young to middle age. In the male groups of 40~49、50~59, 60~69, 70~79 and female groups of 30~39, 40~49, 50~59, 60~69 years old, there were also significant differences in BMD in different age groups of the same sex, and decreased with age. There was significant difference in the incidence of OP between different age groups in the male and female groups. Age was positively related to the incidence of OP (r=0.517 for male and r=0.636 for female). Conclusion: The vertebral BMD derived from QCT for healthy adults in Foshan are associated with sex and age, peaked at 20~29 years old, and decreased with age. The incidence of OP for male and female increased with age from 40~49 years old.

  • [1]
    Consensus development conference: Diagnosis, prophylaxis, and treatment of osteoporosis[J]. American Journal of Medicine, 1993, 94(6): 646-650. DOI: 10.1016/0002-9343(93)90218-E.
    [2]
    中华医学会骨质疏松和骨矿盐疾病分会. 原发性骨质疏松症诊疗指南(2022)[J]. 中国全科医学, 2023,26(14): 1671−1691. doi: 10.12114/j.issn.1007-9572.2023.0121

    Chinese Society of Osteoporosis and Bone Mineral Research. Guidelines for the diagnosis and treatment of primary osteoporosis (2022)[J]. Chinese General Practice, 2023, 26(14): 1671−1691. (in Chinese). doi: 10.12114/j.issn.1007-9572.2023.0121
    [3]
    程晓光, 王亮, 曾强, 等. 中国定量CT(QCT)骨质疏松症诊断指南(2018)[J]. 中国骨质疏松杂志, 2019,25(6): 733−737. doi: 10.3969/j.issn.1006-7108.2019.06.001

    CHENG X G, WANG L, ZENG Q, et al. The China guideline for the diagnosis criteria of osteoporosis with quantitative computed tomography (QCT) (2018)[J]. Chinese Journal of Osteoporosis, 2019, 25(6): 733−737. (in Chinese). doi: 10.3969/j.issn.1006-7108.2019.06.001
    [4]
    中华医学会放射学分会骨关节学组, 中国医师协会放射医师分会肌骨学组, 中华医学会骨科学分会骨质疏松学组, 等. 骨质疏松的影像学与骨密度诊断专家共识[J]. 中国骨质疏松杂志, 2020,26(9): 1249−1256. doi: 10.3969/j.issn.1006-7108.2020.09.001

    Bone and Joint Group of Chinese Society of Radiology, Chinese Medical Association, Musculoskeletal Radiology Society of Chinese Medical Doctors Association, et al. Consensus on the diagnosis of osteoporosis by imaging and bone mineral density measurement[J]. Chinese Journal of Osteoporosis, 2020, 26(9): 1249−1256. (in Chinese). doi: 10.3969/j.issn.1006-7108.2020.09.001
    [5]
    WANG L H, YU W, YIN X J, et al. Prevalence of osteoporosis and fracture in China: The China osteoporosis prevalence study[J]. JAMA Network Open, 2021, 4(8): e2121106. DOI: 10.1001/jamanetworkopen.2021.21106.
    [6]
    中国疾病预防控制中心慢性非传染性疾病预防控制中心, 中华医学会骨质疏松和骨矿盐疾病分会. 中国骨质疏松症流行病学调查报告(2018)[M]. 北京: 人民卫生岀版社, 2021.
    [7]
    王刚, 龙翔宇. 佛山市居民骨质疏松认知情况调查分析[J]. 按摩与康复医学, 2015,(24): 155−156.
    [8]
    中国健康促进基金会基层医疗机构骨质疏松症诊断与治疗专家共识委员会. 基层医疗机构骨质疏松症诊断和治疗专家共识(2021)[J]. 中国骨质疏松杂志, 2021,27(7): 937−944. doi: 10.3969/j.issn.1006-7108.2021.07.001

    Expert Consensus Committee on Diagnosis and Treatment of Osteoporosis in Grassroots Medical Institutions of China Health Promotion Foundation. Expert consensus on the diagnosis and treatment of osteoporosis in primary medical institutions (2021)[J]. Chinese Journal of Osteoporosis, 2021, 27(7): 937−944. (in Chinese). doi: 10.3969/j.issn.1006-7108.2021.07.001
    [9]
    KENDLER D L, BAUER D C. DAVISON K S, et al. Vertebral fractures: Clinical importance and management[J]. American Journal of Medicine, 2016, 129(2): 221.e221−210. DOI: 10.1016/j.amjmed.2015.09.020.
    [10]
    SIRIS E S, ADLER R, BILEZIKIAN J, et al. The clinical diagnosis of osteoporosis: A position statement from the National Bone Health Alliance Working Group[J]. Osteoporos International, 2014, 25(5): 1439−1443. DOI: 10.1007/s00198-014-2655-z.
    [11]
    中国康复医学会骨质疏松预防与康复专业委员会. 骨质疏松性椎体压缩骨折诊治专家共识 (2021版)[J]. 中华医学杂志, 2021,101(41): 3371−3379. doi: 10.3760/cma.j.cn112137-20210625-01436
    [12]
    孙振国, 杨红航, 李恒, 等. 腰椎定量CT对骨质疏松性胸腰椎骨折行椎体成形术的指导意义[J]. 中国骨伤, 2020,33(2): 111−115. doi: 10.12200/j.issn.1003-0034.2020.02.004

    SUN Z G, YANG H H, LI H, et al. Guiding significance of lumbar quantitative computed tomography in percutaneous vertebroplasty for osteoporotic vertebral compression fractures[J]. China Journal of Orthopaedics and Traumatology, 2020, 33(2): 111−115. (in Chinese). doi: 10.12200/j.issn.1003-0034.2020.02.004
    [13]
    ZENG Q, LI N, WANG Q, et al. The prevalence of osteoporosis in china, a nationwide, multicenter dxa survey[J]. Journal of Bone and Mineral Research, 2019, 34(10): 1789−1797. DOI: 10.1002/jbmr.3757.
    [14]
    中华医学会骨质疏松和骨矿盐疾病分会. 中国骨质疏松症流行病学调查及“健康骨骼”专项行动结果发布[J]. 中华骨质疏松和骨矿盐疾病杂志, 2019,12(4): 317−318. doi: 10.3969/j.issn.1674-2591.2019.04.001
    [15]
    程晓光, 董剩勇, 王亮, 等. 应用双能X线骨密度仪调查中国人群骨密度水平和骨质疏松症患病率−多中心大样本体检人群调查[J]. 中华健康管理学杂志, 2019,13(1): 51−58. doi: 10.3760/cma.j.issn.1674?0815.2019.01.007

    CHENG X G, DONG S Y, WANG L, et al. Prevalence of osteoporosis in China: A multicenter, large-scale survey of a health checkup population[J]. Chinese Journal of Health Management, 2019, 13(1): 51−58. (in Chinese). doi: 10.3760/cma.j.issn.1674?0815.2019.01.007
    [16]
    马远征, 王以朋, 刘强, 等. 中国老年骨质疏松症诊疗指南(2018)[J]. 中国骨质疏松杂志, 2018,24(12): 1541−1567. doi: 10.3969/j.issn.1006-7108.2018.12.001

    MA Y Z, WANG Y P, LIU Q, et al. 2018 China guideline for diagnosis and treatment of senile osteoporosis[J]. Chinese Journal of Osteoporosis, 2018, 24(12): 1541−1567. (in Chinese). doi: 10.3969/j.issn.1006-7108.2018.12.001
    [17]
    XU H, CHEN J X, GONG J, et al. Normal reference for bone density in healthy Chinese children[J]. Journal of Clinical Densitometry, 2007, 10(3): 266−275. DOI: 10.1016/j.jocd.2007.05.005.
    [18]
    KNAPP K M, BLAKE G M, SPECTOR T D, et al. Can the WHO definition of osteoporosis be applied to multi-site axial transmission quantitative ultrasound?[J]. Osteoporosis International, 2004, 15(5): 367−374. doi: 10.1007/s00198-003-1555-4
    [19]
    张智海, 刘忠厚, 石少辉, 等. 中国大陆地区以-2.5 SD为诊断的骨质疏松症发病率文献回顾性研究[J]. 中国骨质疏松杂志, 2015,21(1): 1−7, 24. doi: 10.3969/j.issn.1006-7108.2015.01.001

    ZHANG Z H, LIU Z H, SHI S H, et al. A retrospective literature study of osteoporosis incidence based on -2.5 SD criteria in mainland China[J]. Chinese Journal of Osteoporosis, 2015, 21(1): 1−7, 24. (in Chinese). doi: 10.3969/j.issn.1006-7108.2015.01.001
    [20]
    XU X M, LI N, LI K, et al. Discordance in diagnosis of osteoporosis by quantitative computed tomography and dual-energy X-ray absorptiometry in Chinese elderly men[J]. Journal of Orthopaedic Translation, 2019, 18: 59−64. DOI: 10.1016/j.jot.2018.11.003.
    [21]
    ENGELKE K, ADAMS J E, ARMBRECHT G, et al. Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: The 2007 ISCD official positions[J]. Journal of Clinical Densitometry, 2008, 11(1): 123162. DOI: 10.1016/j.jocd.2007.12.010.
    [22]
    American College of Radiology. ACR-SPR-SSR practice parameter for the performance of musculoskeletal quantitative computed tomography (QCT) [EB/OL]. https://www.acr.org/-/media/ACR/Files/Practice-Parameters/qct.pdf?la=en.
    [23]
    李凯, 陈捷, 赵林芬, 等. 中国人群定量CT(QCT)脊柱骨密度正常参考值的建立和骨质疏松症QCT诊断标准的验证[J]. 中国骨质疏松杂志, 2019,25(9): 1257−1262, 1272. doi: 10.3969/j.issn.1006-7108.2019.09.011

    LI K, CHEN J, ZHAO L F, et al. The establishment of QCT spinal vBMD reference database and the validation of the diagnosis criteria of osteoporosis with QCT for Chinese[J]. Chinese Journal of Osteoporosis, 2019, 25(9): 1257−1262, 1272. (in Chinese). doi: 10.3969/j.issn.1006-7108.2019.09.011
    [24]
    王玲, 查晓娟, 杜霞, 等. 中国人群定量CT椎体骨密度正常参考数据库及与BMI、年龄的相关性: 基于中国健康定量CT大数据队列研究[J]. 中华骨质疏松和骨矿盐疾病杂志, 2022,15(1): 36−42. doi: 10.3969/j.issn.1674-2591.2022.01.007

    WANG L, ZHA X J, DU X, et al. Quantitative CT spinal vBMD reference database for Chinese and the associations with BMI and age: Based on the China biobank study[J]. Chinese Journal of Osteoporosis and Bone Mineral Research, 2022, 15(1): 36−42. (in Chinese). doi: 10.3969/j.issn.1674-2591.2022.01.007
    [25]
    舒意, 杨沛, 廖紫祾, 等. 一站式低剂量扫描在胸部及腰椎QCT体检人群中的应用[J]. CT理论与应用研究, 2022, 31(2): 244-250. DOI: 10.15953/j.1004-4140.2022.31.02.12.

    SHU Y, YANG P, LIAO Z L, et al. To explore the low-dose CT and QCT “one-stop-shop” scan technology for physical examination crowd[J]. CT Theory and Applications, 2022, 31(2): 244-250. DOI: 10.15953/j. 1004-4140.2022. 31.02. 12. (in Chinese).
    [26]
    王勇朋, 阳琰, 何生生, 等. 低剂量胸部CT与QCT椎体骨密度测量一站式扫描可行性研究[J]. 放射学实践, 2018,33(11): 1194−1197. doi: 10.13609/j.cnki.1000-0313.2018.11.017

    WANG Y P, YANG Y, HE S S, et al. Low-dose chest CT and QCT "one-stop-shop" scan technology: A feasibility study[J]. Radiologic Practice, 2018, 33(11): 1194−1197. (in Chinese). doi: 10.13609/j.cnki.1000-0313.2018.11.017
    [27]
    刘桐希, 李香凝, 曾庆, 等. 胸部低剂量CT筛查联合定量CT骨密度测量在健康体检中的应用[J]. 中华健康管理学杂志, 2018,12(3): 269−271. doi: 10.3760/cma.j.issn.1674-0815.2018.03.015

    LIU T X, LI X N, ZENG Q, et al. Clinical use of low-dose computed tomography chest screening combined with quantitative computed tomography in the screening of osteoporosis in adults[J]. Chinese Journal of Health Management, 2018, 12(3): 269−271. (in Chinese). doi: 10.3760/cma.j.issn.1674-0815.2018.03.015
    [28]
    CHENG X, ZHAO K, ZHA X, et al. Opportunistic screening using low dose CT and the prevalence of osteoporosis in China: A nationwide, multicenter study[J]. Journal of Bone and Mineral Research, 2021, 36(3): 427−435. DOI: 10.1002/jbmr.4187.
    [29]
    姜文蓁, 张宇威, 崔效楠, 等. 胸部低剂量CT结合定量CT测量下段胸椎骨密度诊断骨质疏松[J]. 中国医学影像技术, 2022,38(5): 734−738. doi: 10.13929/j.issn.1003-3289.2022.05.024

    JIANG W Z, ZHANG Y W, CUI X N, et al. Low-dose CT combined with quantitative CT measurement of bone mineral density of lower thoracic vertebri for diagnosing osteoporosis[J]. Chinese Journal of Medical Imaging Technology, 2022, 38(5): 734−738. (in Chinese). doi: 10.13929/j.issn.1003-3289.2022.05.024
    [30]
    滕剑, 彭飞, 张羽, 等. 定量CT测量胸椎骨密度诊断骨质疏松的初步研究[J]. 实用放射学杂志, 2022,38(4): 621−624. doi: 10.3969/j.issn.1002-1671.2022.04.026

    TENG J, PENG F, ZHANG Y, et al. A preliminary study on the diagnosis of osteoporosis based on quantitative CT measurement of thoracic spine bone mineral density[J]. Journal of Practical Radiology, 2022, 38(4): 621−624. (in Chinese). doi: 10.3969/j.issn.1002-1671.2022.04.026
    [31]
    陈文清, 李建军, 陈峰, 等. 海南地区汉族健康成年人骨密度CT定量研究[J]. 海南医学, 2017,28(20): 3342−3345. doi: 10.3969/j.issn.1003-6350.2017.20.025

    CHEN W Q, LI J J, CHEN F, et al. Quantitative CT study of bone mineral density for Han nationalities healthy adults in Hainan province[J]. Hainan Medical Journal, 2017, 28(20): 3342−3345. (in Chinese). doi: 10.3969/j.issn.1003-6350.2017.20.025
    [32]
    陈刘萍, 翟建, 冉利梅, 等. 中国成年男性人群脊柱定量CT骨密度参考值和地区差异[J]. 中华健康管理学杂志, 2022,16(9): 604−609. doi: 10.3760/cma.j.cn115624-20220516-00371

    CHEN L P, ZHAI J, RAN L M, et al. Normal reference and regional variation of spinal bone mineral density under the quantitative CT in Chinese male population[J]. Chinese Journal of Health Management, 2022, 16(9): 604−609. (in Chinese). doi: 10.3760/cma.j.cn115624-20220516-00371
    [33]
    金鹰, 赵凯平, 瞿建, 等. 基于定量CT的中国健康成年女性腰椎骨密度正常参考值及地区差异[J]. 中华健康管理学杂志, 2022,16(9): 610−615. doi: 10.3760/cma.j.cn115624-20220321-00186

    JIN Y, ZHAO K P, QU J, et al. Reference value of lumbar spine bone mineral density and regional differences based on quantitative CT examination in healthy adult female in China[J]. Chinese Journal of Health Management, 2022, 16(9): 610−615. (in Chinese). doi: 10.3760/cma.j.cn115624-20220321-00186

Catalog

    Article views (164) PDF downloads (27) Cited by()
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return