ISSN 1004-4140
CN 11-3017/P
SHEN X N, ZHOU Z H, WANG Y T, et al. The Impact of CARE kV Technology on Radiation Dose in Coronary Computed Tomography Angiography[J]. CT Theory and Applications, xxxx, x(x): 1-6. DOI: 10.15953/j.ctta.2024.336. (in Chinese).
Citation: SHEN X N, ZHOU Z H, WANG Y T, et al. The Impact of CARE kV Technology on Radiation Dose in Coronary Computed Tomography Angiography[J]. CT Theory and Applications, xxxx, x(x): 1-6. DOI: 10.15953/j.ctta.2024.336. (in Chinese).

The Impact of CARE kV Technology on Radiation Dose in Coronary Computed Tomography Angiography

More Information
  • Received Date: December 29, 2024
  • Revised Date: April 10, 2025
  • Accepted Date: April 15, 2025
  • Available Online: May 18, 2025
  • Objective: To investigate the impact of CARE kV technology on radiation dose in coronary computed tomography angiography (CCTA). Methods: This retrospective study analyzed data from 1,529 patients who underwent CCTA at The First Affiliated Hospital of Chongqing Medical University between December 2023 and December 2024. All scans utilized CARE kV technology, with patients stratified by automatically selected kV values. Radiation dose metrics recorded included the volume CT dose index (CTDIvol), dose-length product (DLP), size-specific dose estimate (SSDE), effective dose derived from DLP (ED_DLP), and Monte Carlo simulation-based effective dose (ED_Radimetrics). Dose ratio differences were characterized by SSDE/CTDIvol and ED_Radimetrics/ED_DLP. Group comparisons were conducted using Kruskal–Wallis H tests with Bonferroni correction, while associations between kV and dose metrics/ratios were assessed with Spearman correlation analysis. Results: Patients were categorized into four kV groups: 70kV (n=815), 80kV (n=541), 90kV (n=67), and 100kV (n=106). Significant intergroup differences (all P < 0.05) were observed in all dose metrics (CTDIvol, DLP, SSDE, ED_DLP, ED_Radimetrics) and dose ratios (SSDE/CTDIvol, ED_Radimetrics/ED_DLP). Spearman analysis revealed moderate positive correlations between kV and CTDIvol (ρ=0.52, P < 0.05), DLP (ρ=0.49, P < 0.05), SSDE (ρ=0.54, P < 0.05), ED_DLP (ρ=0.49, P < 0.05), and ED_Radimetrics (ρ=0.46, P < 0.05). A weak negative correlation was found between kV and SSDE/CTDIvol (ρ=−0.30, P < 0.05), while a negligible positive correlation was observed between kV and ED_Radimetrics/ED_DLP (ρ=0.07, P < 0.05). Conclusion: CARE kV technology effectively reduces radiation dose in CCTA. All dosimetric metrics exhibit moderate positive correlations with kV, underscoring kV selection as a critical determinant of dose control. Conventional metrics CTDIvol and ED_DLP systematically underestimate actual radiation dose levels, with the extent of underestimation showing minimal dependence on the CARE kV-selected kV values. We recommend integrating SSDE and ED_Radimetrics into standardized dose management protocols to enhance patient-specific radiation protection and risk stratification.

  • [1]
    YOSHIDA K, TANABE Y, HOSOKAWA T, et al. Coronary computed tomography angiography for clinical practice[J]. Japanese Journal of Radiology, 2024, 42(6): 555-580. DOI: 10.1007/s11604-024-01543-1.
    [2]
    王曼, 王怡宁, 于敏, 等. 人工智能成像优化技术在冠状动脉CT血管成像的初步应用研究[J]. 中华放射学杂志, 2020, 54(5): 460-466. DOI: 10.3760/cma.j.cn112149-20191219-00990.

    WANG M, WANG Y N, YU M, et al. Preliminary application of artificial intelligence-based image optimization in coronary CT angiography[J]. Chinese Journal of Radiology, 2020, 54(5): 460-466. DOI: 10.3760/cma.j.cn112149-20191219-00990.
    [3]
    AGHAYEV A, MURPHY D J, KERALIYA A R, et al. Recent developments in the use of computed tomography scanners in coronary artery imaging[J]. Expert Review of Medical Devices, 2016, 13(6): 545-553. DOI: 10.1080/17434440.2016.1184968.
    [4]
    闫昕, 赵建华. 基于CCTA的冠状动脉周围脂肪组织影像组学研究进展[J]. CT理论与应用研究, 2024, 33(4): 531-538. DOI: 10.15953/j.ctta.2023.179.

    YAN, X ZHAO J H. Research progress of pericoronary adipose tissue radiomics based on coronary computed tomography angiography[J]. CT Theory and Applications, 2024, 33(4): 531-538. DOI: 10.15953/j.ctta.2023.179.
    [5]
    张艳, 吴金霞, 王莹, 等. 基于体重的低电压和低碘流率在冠状动脉CT血管成像中的应用[J]. 中华医学杂志, 2024, 104(10): 751-757. DOI: 10.3760/cma.j.cn112137-20230728-01109.

    YAN Z, J WU J X, WANG Y, et al. The application of setting tube voltage and iodine delivery rate in weight-grouped for reducing the radiation and contrast medium dose in coronary CT angiography[J]. National Medical Journal of China, 2024, 104(10): 751-757. DOI: 10.3760/cma.j.cn112137-20230728-01109.
    [6]
    LIN Z X, ZHOU F, SCHOEPF U J, et al. Tube voltage, DNA double-strand breaks, and image quality in coronary CT angiography[J]. Korean Journal of Radiology, 2020, 21(8): 967. DOI: 10.3348/kjr.2019.0932.
    [7]
    CHA M J, KIM S M, AHN T R, et al. Comparing feasibility of low-tube-voltage protocol with low-iodine-concentration contrast and high-tube-voltage protocol with high-iodine-concentration contrast in coronary computed tomography angiography[J]. PLOS ONE, 2020, 15(7): e236108. DOI: 10.1371/journal.pone.0236108.
    [8]
    ZHANG J, KANG S, HAN D, et al. Application of intelligent optimal kV scanning technology (CARE kV) in dual-source computed tomography (DSCT) coronary angiography[J]. International journal of clinical and experimental medicine, 2015, 8(10): 17644-17653.
    [9]
    刘丹丹, 牛延涛. 不同扫描中心结合自动管电流调制技术和自动管电压调制技术在CT扫描中对辐射剂量影响的模体研究[J]. 中华放射医学与防护杂志, 2018, 38(8): 621-625. DOI: 10.3760/cma.j.issn.0254-5098.2018.08.012.

    LIU D D, NIU Y T. The phantom study on the influence of radiation dose in CT scanning with different scanning centers combined with the techniques of the ATCM and CARE kV[J]. Chinese Journal of Radiological Medicine and Protection, 2018, 38(8): 621-625. DOI: 10.3760/cma.j.issn.0254-5098.2018.08.012.
    [10]
    王俊琴, 刘太峰, 张海燕. 智能最佳管电压联合自动管电流在降低胸部CT扫描剂量中的应用[J]. 临床放射学杂志, 2019, 38(5): 931-935. DOI: DOI: 10.13437/j.cnki.jcr.2019.05.043.

    WANG J Q, LIU T F, ZHANG H Y. Application of the technique of CARE kV combined with CARE dose 4D in reducing radiation dosage ofchest CT scanning[J]. Journal of Clinical Radiology, 2019, 38(5): 931-935. DOI: 10.13437/j.cnki.jcr.2019.05.043.
    [11]
    TIAN X, CHANG Z, DILIXIATI S, et al. Optimizing image quality and minimizing radiation dose in pediatric abdominal multiphase contrast-enhanced computed tomography: a study on CARE kV and CARE Dose 4D[J]. Quantitative imaging in medicine and surgery, 2024, 14(2): 1985-1993. DOI: 10.21037/qims-23-1181.
    [12]
    ELLER A, WUEST W, SCHARF M, et al. Attenuation-based automatic kilovolt (kV)-selection in computed tomography of the chest: Effects on radiation exposure and image quality[J]. European Journal of Radiology, 2013, 82(12): 2386-2391. DOI: 10.1016/j.ejrad.2013.08.043.
    [13]
    王坤, 金倞, 李骋, 等. Care kV技术在双源CT胸痛三联CT血管造影中对图像质量及辐射剂量的影响[J]. 复旦学报(医学版), 2022, 49(4): 574-581. DOI: 10.3969/j.issn.1672-8467.2022.04.015.

    WANG K, JIN L, LI C, et al. Effect of care kV technology on image quality and radiation dose in dual-source CT triple rule out CT angiography for chest pain[J]. Fudan University Journal of Medical Sciences, 2022, 49(4): 574-581. DOI: 10.3969/j.issn.1672-8467.2022.04.015.
    [14]
    KOPP M, LOEWE T, WUEST W, et al. Individual calculation of effective dose and risk of malignancy based on monte carlo simulations after whole body computed tomography[J]. Scientific Reports, 2020, 10(1). DOI: 10.1038/s41598-020-66366-2.
    [15]
    McCOLLOUGH C, BAKALYAR D M, BOSTANI M, et al. Use of water equivalent diameter for calculating patient size and Size-Specific Dose Estimates (SSDE) in CT: The Report of AAPM task group 220[J]. AAPM report, 2014: 6-23.
    [16]
    McCOLLOUGH C, CODY D, EDYVEAN S. The measurement, reporting, and management of radiation dose in CT(2008)[R]. Report of AAPM Task Group 23. 2008, ISBN: 978-1-888340-73-0. https://doi.org/10.37206/97.
    [17]
    中华医学会放射学分会心胸学组, 中华放射学杂志 心脏冠状动脉多排CT临床应用指南写作专家组. 心脏冠状动脉CT血管成像技术规范化应用中国指南[J]. 中华放射学杂志, 2017, 51(10): 732-743. DOI: 10.3760/j.issn.1005-1201.2017.10.004.
    [18]
    FAN Y, QIN T, SUN Q, et al. A review of factors affecting radiation dose and image quality in coronary CTA performed with wide-detector CT[J]. Tomography, 2024, 10(11): 1730-1743. DOI: 10.3390/tomography10110127.
    [19]
    SUN J, ZHANG Q, ZHOU Z, et al. Optimal tube voltage for abdominal enhanced CT in children: a self-controlled study[J]. Acta Radiologica, 2020, 61(1): 101-109. DOI: 10.1177/0284185119847683.
    [20]
    WANG Y, ZHANG Y, DI A, et al. Feasibility of weight-based tube voltage and iodine delivery rate for coronary artery CT angiography[J]. Current medical imaging, 2024. DOI: 10.2174/0115734056287292240206115534.
    [21]
    ZHANG Y, WANG Y, LI J, et al. Refining the radiation and contrast medium dose in weight‐grouped scanning protocols for coronary CT angiography[J]. Journal of applied clinical medical physics, 2023, 24(7): e14041. DOI: 10.1002/acm2.14041.
    [22]
    XU J, HE X, XIAO H, et al. Comparative study of volume computed tomography dose index and size-specific dose estimate head in computed tomography examination for adult patients based on the mode of automatic tube current modulation[J]. Medical science monitor: international medical journal of experimental and clinical research, 2019, 25: 71-76. DOI: 10.12659/MSM.913927.
    [23]
    PARIKH R A, WIEN M A, NOVAK R D, et al. A comparison study of size-specific dose estimate calculation methods[J]. Pediatric Radiology, 2018, 48(1): 56-65. DOI: 10.1007/s00247-017-3986-7.
    [24]
    FU W, RIA F, SEGARS W P, et al. Patient-informed organ dose estimation in clinical CT: Implementation and effective dose assessment in 1048 clinical patients[J]. American Journal of Roentgenology, 2021, 216(3): 824-834. DOI: 10.2214/AJR.19.22482.
    [25]
    PROTECTION I C O R. The 2007 Recommendations of the International Commission on Radiological Protection. ICRP Publication 103[J]. Annals of the ICRP, 2007, 37(2/4).
    [26]
    BRINDHABAN A. Size-specific dose estimates calculated using patient size measurements from scanned projection radiograph in high-resolution chest computed tomography[J]. Journal of medical radiation sciences, 2024. DOI: 10.1002/jmrs.830.
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