ISSN 1004-4140
CN 11-3017/P
YU Meiyan, REN Mengmeng, HUO Jianwei, LIU Junlian, HONG Yueying, ZHANG Yanan, LI Chen, LI Junqiu. The Whole-spine CT Findings in SAPHO Syndrome[J]. CT Theory and Applications, 2021, 30(4): 503-510. DOI: 10.15953/j.1004-4140.2021.30.04.11
Citation: YU Meiyan, REN Mengmeng, HUO Jianwei, LIU Junlian, HONG Yueying, ZHANG Yanan, LI Chen, LI Junqiu. The Whole-spine CT Findings in SAPHO Syndrome[J]. CT Theory and Applications, 2021, 30(4): 503-510. DOI: 10.15953/j.1004-4140.2021.30.04.11

The Whole-spine CT Findings in SAPHO Syndrome

More Information
  • Received Date: April 27, 2021
  • Available Online: September 23, 2021
  • Objective: To study the CT characteristics of spinal lesions in SAPHO syndrome patients,and quantitative analysis was performed. Methods: Twenty young patients with SAPHO syndrome were enrolled and underwent low-dose CT (LDCT) examination. The CT Syndesmophyte Score (CTSS) of ankylosing spondylitis in 2017 was used to evaluate the whole spine. We assessed the clinical data, the distribution characteristics and degree of lesions involved spine. Results: Eighteen patients had spinal lesions on CT. 0ne hundred and forty-five units were involved. The lesions were detected mainly in the posterior corner 2.1% (68/3312), There are no statistical differences in distribution between the affected vertebras with "kissing" appearance 9.9% (82/828) and "non-kissing" appearance 7.6% (63/828). One intervertebral disc space was narrowed. There is no paraspinal soft-tissue involvement. Distribution of lesions in cervical vertebrae, thoracic vertebrae and lumbar vertebrae were no statistical difference (P>0.05). Lesions mainly occurred in thoracic vertebras and lumbar vertebras. There was no association between the CTSS and the course of the disease. Conclusion: lDCT can accurately reflect the characteristic performance of the whole spine lesions of SAPHO syndrome patients. The common sites were the posterior corner of thoracic vertebras and lumbar vertebras, and CTSS could not reflect the course of disease.
  • [1]
    CHAMOT A M, BENHAMOU C L, KAHM M F, et al. Acne pustulosis hyperostosis osteitis syndrome. Results of a national survey:85 cases[J]. Revue du Rhumatisme et des Maladies Osteo-Articulaires, 1987, 54(3):187-196.
    [2]
    CAO Y, LI C, YANG Q, et al. Three patterns of osteoarticular involvement in SAPHO syndrome:A cluster analysis based on whole body bone scintigraphy of 157 patients[J]. Rheumatology (Oxford), 2019, 58(6):1047-1055.
    [3]
    CAO Y, LI C, XU W, et al. Spinal and sacroiliac involvement in SAPHO syndrome:A single center study of a cohort of 354 patients[J]. Seminars in Arthritis and Rheumatism, 2019, 48(6):990-996.
    [4]
    XU W, LI C, ZHAO X, et al. Whole-spine computed tomography findings in SAPHO syndrome[J]. Journal of Rheumatology, 2017, 44(5):648-654.
    [5]
    JURIK A G, KLICMAN R F, SIMONI P, et al. SAPHO and CRMO:The value of imaging[J]. Semininars Musculoskeletal Radiololoy, 2018, 22(2):207-224.
    [6]
    NGUYEN M T, BORCHERS A, SELMI C, et al. The SAPHO syndrome[J]. Seminars in Arthritis and Rheumatism, 2012, 42(3):254-265.
    [7]
    de KONING A, de BRUIN F, van den BERG R, et al. Low-dose CT detects more progression of bone formation in comparison to conventional radiography in patients with ankylosing spondylitis:Results from the SIAS cohort[J]. Annals of the Rheumatic Diseases, 2018, 77(2):293-299.
    [8]
    de Bruin F, de Koning A, van den Berg R, et al. Development of the CT syndesmophyte score (CTSS) in patients with ankylosing spondylitis:Data from the SIAS cohort[J]. Annals of the Rheumatic Diseases, 2018, 77(3):371-377.
    [9]
    于梅艳, 李俊秋, 张亚男, 等. SAPHO综合征骶髂关节病变的CT表现[J]. CT理论与应用研究, 2020, 29(3):355-360.

    DOI:10.15953/j.1004-4140.2020.29.03.12. YU M Y, LI J Q, ZHANG Y N, et al. The CT manifestations of SAPHO syndrome with sacroiliac joint involvement[J]. CT Theory and Applications, 2020, 29(3):355-360. DOI:10.15953/j.1004-4140.2020.29.03.12. (in Chinese).
    [10]
    于梅艳, 唐莹, 刘军莲, 等. 基于22例SAPHO综合征患者全脊柱病变的MRI表现[J]. 磁共振成像, 2020, 11(12):1143-1147.

    YU M Y, TANG Y, LIU J L, et al. MRI findings of whole spinal in 22 patients with SAPHO syndrome[J]. Chinese Journal of Magnetic Resonance Imaging, 2020, 11(12):1143-1147. (in Chinese).
    [11]
    刘曦, 徐文睿, 邵暇荔, 等. 伴慢性背部疼痛SAPHO综合征患者全脊柱及骶髂关节MRI表现[J]. 中华临床免疫和变态反应杂志, 2021, 15(2):159-165.

    LIU X, XU W R, SHAO X L, et al. Whole spine and sacroiliac joint MRI findings in SAPHO syndrome patients with chronic back pain[J]. Chinese Journal of Allergy Clinical Immunology, 2021, 15(2):159-165. (in Chinese).
    [12]
    徐文睿. SAPHO综合征患者脊柱及骶髂关节病变的影像学表现及临床应用[D]. 北京:北京协和医学院, 2017. XU W R. Imaging manifestations and clinical application of spinal and sacroiliac joint lesions in patients with SAPHO syndrome[D]. Beijing:Peking Union Medical College, 2017. (in Chinese).
    [13]
    ZIMMERMANN P, CURTIS N. The role of Cutibacterium acnes in auto-inflammatory bone disorders[J]. European Journal of Pediatrics, 2019, 178(1):89-95.
    [14]
    DAOUSSIS D, KONSTANTOPOULOU G, KRANIOTIS P, et al. Biologics in SAPHO syndrome:A systematic review[J]. Seminars in arthritis and rheumatism, 2019, 48(4):618-625.
    [15]
    PAPARO F, REVELLI M, SEMPRINI A, et al. Seronegative spondyloarthropathies:What radiologists should know[J]. Radiologia Medica, 2014, 119(3):156-163.
    [16]
    COLINA M, LO MONACO A, KHODEIR M, et al. Propionibacterium acnes and SAPHO syndrome:A case report and literature review[J]. Clinical and Experimental Rheumatology, 2007, 25(3):457-460.
    [17]
    SU C, SHEN Y, LIAO H, et al. SAPHO syndrome with enthesopathy[J]. British Medical Journal Case Reports, 2019, 12(1):e225929. DOI: 10.1136/bcr-2018-225929.
    [18]
    MCGAUVRAN A, KOTSENAS A, DIEHN F, et al. SAPHO syndrome:Imaging findings of vertebral involvement[J]. American Journal of Neuroradiology, 2016, 37(8):1567-1572.
    [19]
    YU L, KASSER J R, O'ROURKE E, et al. Chronic recurrent multifocal osteomyelitis:Association with vertebra plana[J]. Journal of Bone and Joint Surgery, 1989, 71(1):105-112.
    [20]
    LI Y, LIU G, ZHAO Y, et al. SAPHO syndrome with pathological fractures of vertebral bodies:A case report[J]. BMC Musculoskeletal Disorders, 2019, 20(1):27.
    [21]
    EDWIN J, AHMED S, VERMA S, et al. Swellings of the sternoclavicular joint:Review of traumatic and non-traumatic pathologies[J]. EFORT Open Reviews, 2018, 3(8):471-484.
  • Related Articles

    [1]XIONG Shan, CHEN Bo, MAO Jie, LIU Sibin, HUANG Yuanyi, CHENG Jianmin. Application of Computer-aided Diagnosis System Based on Deep Learning in Rib Fracture Diagnosis[J]. CT Theory and Applications, 2022, 31(5): 617-622. DOI: 10.15953/j.1004-4140.2022.31.05.08
    [2]YU Meiyan, LI Junqiu, ZHANG Yanan, LI Chen, LIU Junlian, REN Mengmeng, HONG Yueying, HUO Jianwei. The CT Manifestations of SAPHO Syndrome with Sacroiliac Joint Involvement[J]. CT Theory and Applications, 2020, 29(3): 355-360. DOI: 10.15953/j.1004-4140.2020.29.03.12
    [3]LIU Lijun, HAO Fen'e, SUN Zhenting, MENG Lingxin, YANG Zhenxing, ZHAO Lei. Computer-aided Detection Low-dose CT for Early Lung Cancer Screening: A Feasibility Study[J]. CT Theory and Applications, 2019, 28(1): 39-44. DOI: 10.15953/j.1004-4140.2019.28.01.04
    [4]ZHU Hua-qiang, LIU Si-run, QIU Jian, LUO Dong-mei, ZHOU De-ming. X-ray and CT Image Analysis of Pelvic Fractures[J]. CT Theory and Applications, 2011, 20(1): 83-90.
    [5]YU Hong-sheng, JI Liu-zhou. Diagnosis of Esophageal Cancer by X-ray Barium Meal and CT Scan[J]. CT Theory and Applications, 2009, 18(3): 102-109.
    [6]WANG Xue-li. Spatial Resolution and Fourier Analysis for X-ray Medical Device[J]. CT Theory and Applications, 2003, 12(4): 36-41.
    [7]HAN Xiao-mian, TIAN Ben-xiang, YUAN Ling-jin. A Comparative Study of X-ray and CT in Hydrothorax[J]. CT Theory and Applications, 2003, 12(3): 34-35.
    [8]HUANG Shao-quan, TAN Jiang-cheng, CHEN Shu-ke, LONG Hai-dan. X-ray and CT study of esophageal cancer[J]. CT Theory and Applications, 2003, 12(3): 31-33.
    [9]Wei Ruili, Cheng Jianmin. X-ray and CT Findings in Mucoceles of Frontal and Ethmoid Sinuses[J]. CT Theory and Applications, 2000, 9(4): 28-31.
    [10]Li Yubin, Li Xiangliang, Zhang Kuixiang, Cao Xulong. X-Ray Computed Micro-tomography(CMT) and Its Application to Petroleum Research[J]. CT Theory and Applications, 2000, 9(3): 35-40.
  • Cited by

    Periodical cited type(3)

    1. 陈乃刚,李忱,杨强,尹丹,张媛,魏淑凤,张士朋. CT韧带骨赘评分在SAPHO综合征中的应用. 临床放射学杂志. 2024(01): 116-119 .
    2. 崔璨,李俊秋,于梅艳,温庆祥. SAPHO综合征的全身骨显像及SPECT/CT影像分析. 分子影像学杂志. 2024(09): 941-945 .
    3. 谭华清,鲍海华,曹云太,夏弘婧,付诗晗. MRI与CT在SAPHO综合征诊断中的应用分析. 磁共振成像. 2023(11): 108-112 .

    Other cited types(0)

Catalog

    Article views (205) PDF downloads (16) Cited by(3)
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return