Comparative Study of Vertebral-basilar Artery Stenosis Diagnosed by 3D-TOP-MRA and DSA to Patients with Posterior Circulation Ischemia

Objective: To the diagnostic value of magnetic resonance angiography(3D-TOP-MRA) in detecting the posterior circulation ischemia(PCI), and utilize digital subtraction angiography(DSA) as the gold standard. Methods: 80 PCI patients' vertebral-basilar artery was examined both by DSA and 3D-TOP-MRA. And the sensitivity, specificity of 3D-TOP-MRA was compared with DSA. Results: 3D-TOP-MRA had a pooled sensitivity of 88.23% for artery stenosis, and the sensitivity of mild, moderate, severe stenosis and occlusion were 57.89%, 96.30%, 85.71% and 100%, respectively;3D-TOP-MRA had a pooled specificity of 66.67%, and the specificity of mild, moderate, severe stenosis and occlusion were 100%, 96.23%, 92.42% and 100%, respectively. The overall accuracy of 3D-TOP-MRA was 85.00%, and the accuracy of mild, moderate, severe stenosis and occlusion were 90.00%, 96.25%, 91.25% and 100%. Conclusion: 3D-TOP-MRA showed high accuracy and sensitivity for the detection of high-grade PCI stenosis and occlusions.