The Correlation between Epicardial Adipose Tissue Volume Indexed to Body Surface Area and Atrial Fibrillation

Objective:To explore the relationship between the 128 slice spiral CT-derived epicardial adipose tissue volume indexed to body surface area(EATVI) and atrial fibrillation(AF). Methods:Seventy-six patients with atrial fibrillation in our hospital were selected as the atrial fibrillation group, including 45 patients with paroxysmal atrial fibrillation and 31 patients with persistent atrial fibrillation; 60 patients with sinus rhythm were also selected as the sinus rhythm group. 136 patients underwent cardiac coronary CTA imaging, measured EATV of all patients and calculated EATVI,The measurement data of patients with paroxysmal atrial fibrillation and persistent atrial fibrillation were further analyzed and statistically analyzed. Results:EATV value was significantly higher in AF group than in control group((138.54 ±25.79) mL vs(107.56 ±21.17) mL, P<0.001); EATVI value was significantly higher in AF group than in control group((72.54 ±23.21) vs(53.21 ±19.76), P<0.001). EATV((141.72 ±23.26) m L vs(136.23 ±19.76) m L) and EATVI((74.43 ±21.32) vs(70.54 ±19.82)) values tended to be higher in persistent AF group than those in paroxysmal AF group(P>0.05). Correlation analysis showed that EATV and EATVI in patients with atrial fibrillation were significantly positively correlated(r=0.971, P<0.01). ROC curve analysis showed that the area under the curve of EATVI for diagnosing atrial fibrillation was 0.893(95% CI:0.837~0.961). With 61.15 ml/m² as the cut-off value, the sensitivity and specificity of predicting atrial fibrillation were 91.6% and 81.4%, respectively. Logistic multivariate regression analysis showed that EATVI(OR value:1.068; 95% CI:1.021 to 1.107) was an independent risk factor for atrial fibrillation. Conclusion:128-slice spiral CT scan objectively and quantitatively measure EATV. EATV is significantly related to EATVI. The increase in EATVI is closely related to the occurrence of atrial fibrillation, but there is no significant difference in EATV and EATVI between patients with different types of atrial fibrillation.