Discussion on the Effect of Different Concentrations of Contrast Media on CT Imaging of Hepatic Veins Based on BSA and Fixed Iodine Rate

Objective: To explore the effects of different concentrations of contrast agents on the quality of CT hepatic venous imaging based on body surface area (BSA) and fixed iodine rate administration. Method: According to the inclusion criteria, 130 patients were selected and received enhanced upper abdominal CT scan from January to November 2020. According to the different contrast agents, they were divided into high concentration group (62 cases) and low concentration group (68 cases). The contrast agent of the high concentration group was iopamidol (containing iodine 370mg/mL), and the contrast agent of the low concentration group was ioversol (containing iodine 320mg/mL). To calculate the total amount of iodine based on BSA. fixed iodine rate administration, and triple-phase enhanced CT scans. Hepatic vein phase data were selected for reconstruction of hepatic vein vessels, and image quality was evaluated. CT values and standard deviations of hepatic vein and liver parenchyma of the two groups of images were measured. Signal-to-noise ratio (SNR) and contrastive noise ratio (CNR) were calculated, and image quality was evaluated subjectively. The independent sample t test was used to compare the differences in objective evaluation indicators between the two groups, and the Mann-Whitney U test was used to compare the differences in subjective scores. Results: The image scores of high and low concentration groups were (3.74±0.47) points and (3.77±0.53) points, respectively, with no statistical significance; There were no significant differences in CT values, SD values, SNR values of the left, middle and right branches of hepatic vein and liver parenchyma at the same level between the two groups. Conclusion: Based on BSA and fixed iodine rate injection contrast agent, the effect of two different concentrations of contrast agent in hepatic venous CT imaging is equally clear and conducive to diagnosis.