The Whole-spine CT Findings in SAPHO Syndrome

Objective: To study the CT characteristics of spinal lesions in SAPHO syndrome patients,and quantitative analysis was performed. Methods: Twenty young patients with SAPHO syndrome were enrolled and underwent low-dose CT (LDCT) examination. The CT Syndesmophyte Score (CTSS) of ankylosing spondylitis in 2017 was used to evaluate the whole spine. We assessed the clinical data, the distribution characteristics and degree of lesions involved spine. Results: Eighteen patients had spinal lesions on CT. 0ne hundred and forty-five units were involved. The lesions were detected mainly in the posterior corner 2.1% (68/3312), There are no statistical differences in distribution between the affected vertebras with "kissing" appearance 9.9% (82/828) and "non-kissing" appearance 7.6% (63/828). One intervertebral disc space was narrowed. There is no paraspinal soft-tissue involvement. Distribution of lesions in cervical vertebrae, thoracic vertebrae and lumbar vertebrae were no statistical difference (P>0.05). Lesions mainly occurred in thoracic vertebras and lumbar vertebras. There was no association between the CTSS and the course of the disease. Conclusion: lDCT can accurately reflect the characteristic performance of the whole spine lesions of SAPHO syndrome patients. The common sites were the posterior corner of thoracic vertebras and lumbar vertebras, and CTSS could not reflect the course of disease.